OBJECTIVE: To construct and validate a predictive model for the risk of postoperative constipation in middle-aged and elderly patients with lower limb fractures based on machine learning algorithms, so as to provide decision-making support for clinic...
Parkinson's disease (PD) is a brain disorder, that affects a person's body movement causing stiffness, shaking and imbalance. Earlier detection of PD is a challenging task for researchers. In this paper, earlier detection of PD is performed using the...
Proximal junctional failure (PJF) is a significant mechanical complication following corrective surgery for adult spinal deformity (ASD), often resulting in structural failure at the uppermost instrumented vertebra and necessitating revision surgery....
Hematological biomarkers have emerged as powerful tools in diagnosing Acute Heart Failure (AHF). This study introduces a novel diagnostic framework that integrates Explainable Artificial Intelligence (XAI) with Morris Sensitivity Analysis (MSA) to en...
Biomedical physics & engineering express
Nov 14, 2025
Electrocardiogram (ECG) and phonocardiogram (PCG) have emerged as crucial non-invasive and portable diagnostic modalities for early cardiovascular disease (CVD) screening. Despite the individual merits of these signal modalities in CVD detection, sig...
Proceedings of the National Academy of Sciences of the United States of America
Nov 13, 2025
Covert visual attention allows the brain to select different regions of the visual world without eye movements. Predictive cues of a target location orient covert attention and improve perceptual performance. In most computational models, researchers...
BACKGROUND: Genomic Best Linear Unbiased Prediction (GBLUP) assumes that all SNPs contribute equally to genetic variance, including those with minimal impact, limiting its accuracy. A major challenge in animal breeding is to develop more scientific m...
A high-accuracy DNA-based cancer risk predictor was developed by blending Logistic Regression with Gaussian Naive Bayes, and its hyperparameters were optimized via grid search. Five cancer types (BRCA1, KIRC, COAD, LUAD, PRAD) were classified in a co...
BACKGROUND: Accurate stratification of recurrence risk after curative resection remains a critical challenge in the management of hepatocellular carcinoma (HCC). Dysregulated ceramide (CER) metabolism has been implicated in HCC progression and relaps...
BACKGROUND: Non-ST-segment elevation acute coronary syndrome (NSTE-ACS) is a major contributor to cardiovascular mortality, yet reliable tools for individualized mortality prediction remain limited. Machine learning offers the potential to enhance pr...
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