AIMC Topic: Bile Acids and Salts

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Intrahepatic cholestasis of pregnancy: machine-learning algorithm to predict elevated bile acid based on clinical and laboratory data.

Archives of gynecology and obstetrics
PURPOSE: Applying machine-learning models to clinical and laboratory features of women with intrahepatic cholestasis of pregnancy (ICP) and creating algorithm to identify these patients without bile acid measurements.

Bile acids synthesis decreases after laparoscopic sleeve gastrectomy.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
BACKGROUND: Bariatric surgery is the most effective treatment alternative in morbid obesity. The mechanisms contributing to these benefits remain poorly understood. Bile acids (BAs) are mediators of different regulatory functions in glucose and chole...

Simplifying Diagnosis of Bile Acid Diarrhea With Clinical and Biochemical Measurements on Blood and Single Stool Sample.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
BACKGROUND & AIMS: Diagnosis of bile acid diarrhea (BAD) has been based on 48-hour fecal BA excretion; serum 7αC4 (C4) has been used to screen for BAD. Optimal diagnostic cutoffs for C4 and biochemical measurements in a single stool sample are unknow...

Improvement of solubility and dissolution of ebastine by fabricating phosphatidylcholine/ bile salt bilosomes.

Pakistan journal of pharmaceutical sciences
Although ebastine (EBT) can impede histamine-induced skin allergic reaction and persuade long acting selective H1 receptor antagonistic effects but its poor water solubility circumscribed its clinical application. The main objective of this research ...