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Biological Ontologies

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OBO to UML: Support for the development of conceptual models in the biomedical domain.

Journal of biomedical informatics
A conceptual model abstractly defines a number of concepts and their relationships for the purposes of understanding and communication. Once a conceptual model is available, it can also be used as a starting point for the development of a software sy...

Assessing the practice of biomedical ontology evaluation: Gaps and opportunities.

Journal of biomedical informatics
With the proliferation of heterogeneous health care data in the last three decades, biomedical ontologies and controlled biomedical terminologies play a more and more important role in knowledge representation and management, data integration, natura...

Supporting shared hypothesis testing in the biomedical domain.

Journal of biomedical semantics
BACKGROUND: Pathogenesis of inflammatory diseases can be tracked by studying the causality relationships among the factors contributing to its development. We could, for instance, hypothesize on the connections of the pathogenesis outcomes to the obs...

DMTO: a realistic ontology for standard diabetes mellitus treatment.

Journal of biomedical semantics
BACKGROUND: Treatment of type 2 diabetes mellitus (T2DM) is a complex problem. A clinical decision support system (CDSS) based on massive and distributed electronic health record data can facilitate the automation of this process and enhance its accu...

Labeling for Big Data in radiation oncology: The Radiation Oncology Structures ontology.

PloS one
PURPOSE: Leveraging Electronic Health Records (EHR) and Oncology Information Systems (OIS) has great potential to generate hypotheses for cancer treatment, since they directly provide medical data on a large scale. In order to gather a significant am...

OpenBiodiv-O: ontology of the OpenBiodiv knowledge management system.

Journal of biomedical semantics
BACKGROUND: The biodiversity domain, and in particular biological taxonomy, is moving in the direction of semantization of its research outputs. The present work introduces OpenBiodiv-O, the ontology that serves as the basis of the OpenBiodiv Knowled...

MIRO: guidelines for minimum information for the reporting of an ontology.

Journal of biomedical semantics
BACKGROUND: Creation and use of ontologies has become a mainstream activity in many disciplines, in particular, the biomedical domain. Ontology developers often disseminate information about these ontologies in peer-reviewed ontology description repo...

Brain maps 4.0-Structure of the rat brain: An open access atlas with global nervous system nomenclature ontology and flatmaps.

The Journal of comparative neurology
The fourth edition (following editions in 1992, 1998, 2004) of Brain maps: structure of the rat brain is presented here as an open access internet resource for the neuroscience community. One new feature is a set of 10 hierarchical nomenclature table...

Tackling the challenges of matching biomedical ontologies.

Journal of biomedical semantics
BACKGROUND: Biomedical ontologies pose several challenges to ontology matching due both to the complexity of the biomedical domain and to the characteristics of the ontologies themselves. The biomedical tracks in the Ontology Matching Evaluation Init...