AIMC Topic: Biological Ontologies

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BioFed: federated query processing over life sciences linked open data.

Journal of biomedical semantics
BACKGROUND: Biomedical data, e.g. from knowledge bases and ontologies, is increasingly made available following open linked data principles, at best as RDF triple data. This is a necessary step towards unified access to biological data sets, but this...

Ontology-based literature mining of E. coli vaccine-associated gene interaction networks.

Journal of biomedical semantics
BACKGROUND: Pathogenic Escherichia coli infections cause various diseases in humans and many animal species. However, with extensive E. coli vaccine research, we are still unable to fully protect ourselves against E. coli infections. To more rational...

Organ or not? prolegomenon to organology.

Clinical anatomy (New York, N.Y.)
The definition of an organ is vague, so that listing and classifying human organs is problematic. The classical Greek definition of an organ as an instrumental part of the body has been supplemented in modern biology by stating that organs occupy a h...

Ontogeny and the process of biomineralization in the trichomes of Loasaceae.

American journal of botany
PREMISE OF THE STUDY: South American Loasaceae have a morphologically complex trichome cover, which is characterized by multiple biomineralization. The current study investigates the ontogeny of these complex trichomes and the process of their biomin...

Therapeutic indications and other use-case-driven updates in the drug ontology: anti-malarials, anti-hypertensives, opioid analgesics, and a large term request.

Journal of biomedical semantics
BACKGROUND: The Drug Ontology (DrOn) is an OWL2-based representation of drug products and their ingredients, mechanisms of action, strengths, and dose forms. We originally created DrOn for use cases in comparative effectiveness research, primarily to...

Relating Complexity and Error Rates of Ontology Concepts. More Complex NCIt Concepts Have More Errors.

Methods of information in medicine
OBJECTIVES: Ontologies are knowledge structures that lend support to many health-information systems. A study is carried out to assess the quality of ontological concepts based on a measure of their complexity. The results show a relation between com...

Ontogenetic Shifts in Brain Organization in the Bluespotted Stingray Neotrygon kuhlii (Chondrichthyes: Dasyatidae).

Brain, behavior and evolution
Fishes exhibit lifelong neurogenesis and continual brain growth. One consequence of this continual growth is that the nervous system has the potential to respond with enhanced plasticity to changes in ecological conditions that occur during ontogeny....

The ontogeny of kin-recognition mechanisms in Belding's ground squirrels.

Physiology & behavior
Despite extensive research on the functions and mechanisms of kin recognition, little is known about developmental changes in the abilities mediating such recognition. Belding's ground squirrels, Urocitellus beldingi, use at least two mechanisms of k...

Evaluation Results of an Ontology-based Design Model of Virtual Environments for Upper Limb Motor Rehabilitation of Stroke Patients.

Methods of information in medicine
OBJECTIVES: 1) To enhance the content of an ontology for designing virtual environments (VEs) for upper limb motor rehabilitation of stroke patients according to the suggestions and comments of rehabilitation specialists and software developers, 2) t...

Scientific Reproducibility in Biomedical Research: Provenance Metadata Ontology for Semantic Annotation of Study Description.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Scientific reproducibility is key to scientific progress as it allows the research community to build on validated results, protect patients from potentially harmful trial drugs derived from incorrect results, and reduce wastage of valuable resources...