AIMC Topic: Biological Ontologies

Clear Filters Showing 301 to 310 of 648 articles

Modulated evaluation metrics for drug-based ontologies.

Journal of biomedical semantics
BACKGROUND: Research for ontology evaluation is scarce. If biomedical ontological datasets and knowledgebases are to be widely used, there needs to be quality control and evaluation for the content and structure of the ontology. This paper introduces...

Using classification models for the generation of disease-specific medications from biomedical literature and clinical data repository.

Journal of biomedical informatics
OBJECTIVE: Mining disease-specific associations from existing knowledge resources can be useful for building disease-specific ontologies and supporting knowledge-based applications. Many association mining techniques have been exploited. However, the...

A Machine Learning-based Method for Question Type Classification in Biomedical Question Answering.

Methods of information in medicine
BACKGROUND AND OBJECTIVE: Biomedical question type classification is one of the important components of an automatic biomedical question answering system. The performance of the latter depends directly on the performance of its biomedical question ty...

BioFed: federated query processing over life sciences linked open data.

Journal of biomedical semantics
BACKGROUND: Biomedical data, e.g. from knowledge bases and ontologies, is increasingly made available following open linked data principles, at best as RDF triple data. This is a necessary step towards unified access to biological data sets, but this...

Ontology-based literature mining of E. coli vaccine-associated gene interaction networks.

Journal of biomedical semantics
BACKGROUND: Pathogenic Escherichia coli infections cause various diseases in humans and many animal species. However, with extensive E. coli vaccine research, we are still unable to fully protect ourselves against E. coli infections. To more rational...

Organ or not? prolegomenon to organology.

Clinical anatomy (New York, N.Y.)
The definition of an organ is vague, so that listing and classifying human organs is problematic. The classical Greek definition of an organ as an instrumental part of the body has been supplemented in modern biology by stating that organs occupy a h...

Ontogeny and the process of biomineralization in the trichomes of Loasaceae.

American journal of botany
PREMISE OF THE STUDY: South American Loasaceae have a morphologically complex trichome cover, which is characterized by multiple biomineralization. The current study investigates the ontogeny of these complex trichomes and the process of their biomin...

Therapeutic indications and other use-case-driven updates in the drug ontology: anti-malarials, anti-hypertensives, opioid analgesics, and a large term request.

Journal of biomedical semantics
BACKGROUND: The Drug Ontology (DrOn) is an OWL2-based representation of drug products and their ingredients, mechanisms of action, strengths, and dose forms. We originally created DrOn for use cases in comparative effectiveness research, primarily to...

Relating Complexity and Error Rates of Ontology Concepts. More Complex NCIt Concepts Have More Errors.

Methods of information in medicine
OBJECTIVES: Ontologies are knowledge structures that lend support to many health-information systems. A study is carried out to assess the quality of ontological concepts based on a measure of their complexity. The results show a relation between com...

Ontogenetic Shifts in Brain Organization in the Bluespotted Stingray Neotrygon kuhlii (Chondrichthyes: Dasyatidae).

Brain, behavior and evolution
Fishes exhibit lifelong neurogenesis and continual brain growth. One consequence of this continual growth is that the nervous system has the potential to respond with enhanced plasticity to changes in ecological conditions that occur during ontogeny....