AIMC Topic: National Cancer Institute (U.S.)

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Semiautomated Extraction of Research Topics and Trends From National Cancer Institute Funding in Radiological Sciences From 2000 to 2020.

International journal of radiation oncology, biology, physics
PURPOSE: Investigators and funding organizations desire knowledge on topics and trends in publicly funded research but current efforts for manual categorization have been limited in breadth and depth of understanding. We present a semiautomated analy...

Summary of the National Cancer Institute 2023 Virtual Workshop on Medical Image De-identification-Part 2: Pathology Whole Slide Image De-identification, De-facing, the Role of AI in Image De-identification, and the NCI MIDI Datasets and Pipeline.

Journal of imaging informatics in medicine
De-identification of medical images intended for research is a core requirement for data sharing initiatives, particularly as the demand for data for artificial intelligence (AI) applications grows. The Center for Biomedical Informatics and Informati...

On the Best Way to Cluster NCI-60 Molecules.

Biomolecules
Machine learning-based models have been widely used in the early drug-design pipeline. To validate these models, cross-validation strategies have been employed, including those using clustering of molecules in terms of their chemical structures. Howe...

The potential of AI in cancer care and research.

Biochimica et biophysica acta. Reviews on cancer
Current applications of artificial intelligence (AI), machine learning, and deep learning in cancer research and clinical care are highly diverse-from aiding radiologists in reading medical images to predicting oncoprotein folding and dynamics. The l...

Predicting tumor cell line response to drug pairs with deep learning.

BMC bioinformatics
BACKGROUND: The National Cancer Institute drug pair screening effort against 60 well-characterized human tumor cell lines (NCI-60) presents an unprecedented resource for modeling combinational drug activity.

Complex overlapping concepts: An effective auditing methodology for families of similarly structured BioPortal ontologies.

Journal of biomedical informatics
In previous research, we have demonstrated for a number of ontologies that structurally complex concepts (for different definitions of "complex") in an ontology are more likely to exhibit errors than other concepts. Thus, such complex concepts often ...

Relating Complexity and Error Rates of Ontology Concepts. More Complex NCIt Concepts Have More Errors.

Methods of information in medicine
OBJECTIVES: Ontologies are knowledge structures that lend support to many health-information systems. A study is carried out to assess the quality of ontological concepts based on a measure of their complexity. The results show a relation between com...