Adequate blood supply is critical for normal brain function. Brain vasculature dysfunctions, including stalled blood flow in cerebral capillaries, are associated with cognitive decline and pathogenesis in Alzheimer's disease. Recent advances in imagi...
Experimental biology and medicine (Maywood, N.J.)
Jul 19, 2021
Optical coherence tomography angiography (OCTA) offers a noninvasive label-free solution for imaging retinal vasculatures at the capillary level resolution. In principle, improved resolution implies a better chance to reveal subtle microvascular dist...
BACKGROUND: Renal flare of lupus nephritis (LN) is strongly associated with poor kidney outcomes, and predicting renal flare and stratifying its risk are important for clinical decision-making and individualized management to reduce LN flare.
The need for the estimation of the number of microbubbles (MBs) in cardiopulmonary bypass surgery has been recognized among surgeons to avoid postoperative neurological complications. MBs that exceed the diameter of human capillaries may cause endoth...
PURPOSE: Adaptive optics scanning laser ophthalmoscope (AOSLO) capillary perfusion images can possess large variations in contrast, intensity, and background signal, thereby limiting the use of global or adaptive thresholding techniques for automatic...
To assess the microcirculation in a patient's capillaries, clinicians often use the valuable and non-invasive diagnostic tool of nailfold capillaroscopy (NC). In particular, evaluating the images that result from NC is particularly important for diag...
Recent progress on bioresorbable and bio-compatible miniature systems provides prospects for developing novel nanorobots operating inside the human body. These nanoscale systems are expected to dissolve in vivo and cause no side effect after completi...
Computer methods and programs in biomedicine
Jun 27, 2019
BACKGROUND: Diabetic patients treated with intensive insulin therapies require a tight glycemic control and may benefit from advanced tools to predict blood glucose (BG) concentration levels and hypo/hyperglycemia events. Prediction systems using mac...
BACKGROUND: Assessing the extent of inflammation in peritubular capillaries (PTCs) is important for diagnosing antibody-mediated rejection in kidney transplant biopsies. However, this assessment is time-consuming and suffers from interobserver variab...
OBJECTIVES: Nailfold videocapillaroscopy (NVC) is the gold standard for diagnosing SSc and differentiating primary from secondary RP. The CAPI-Score algorithm, designed for simplicity, classifies capillaroscopy scleroderma patterns (CSPs) using a lim...
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