AIMC Topic: Cell Cycle
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Gene Ontology Consortium: going forward.
Nucleic acids research
Nov 26, 2014
The Gene Ontology (GO; http://www.geneontology.org) is a community-based bioinformatics resource that supplies information about gene product function using ontologies to represent biological knowledge. Here we describe improvements and expansions to...
Deep learning-driven imaging of cell division and cell growth across an entire eukaryotic life cycle.
Molecular biology of the cell
Jun 1, 2025
The life cycle of eukaryotic microorganisms involves complex transitions between states such as dormancy, mating, meiosis, and cell division, which are often studied independently from each other. Therefore, most microbial life cycles are theoretical...
A quantitative characterization of the heterogeneous response of glioblastoma U-87 MG cell line to temozolomide.
Scientific reports
May 8, 2025
Most cancers are genetically and phenotypically heterogeneous. This includes subpopulations of cells with different levels of sensitivity to chemotherapy, which may lead to treatment failure as the more resistant cells can survive drug treatment and ...
Measuring Cell Dimensions in Fission Yeast Using Machine Learning.
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2025
In fission yeast (Schizosaccharomyces pombe), cell length is a crucial indicator of cell cycle progression. Microscopy screens that examine the effect of agents or genotypes suspected of altering genomic or metabolic stability and thus cell size are ...
A quick and reliable image-based AI algorithm for evaluating cellular senescence of gastric organoids.
Cancer biology & medicine
Jun 30, 2023
OBJECTIVE: Organoids are a powerful tool with broad application prospects in biomedicine. Notably, they provide alternatives to animal models for testing potential drugs before clinical trials. However, the number of passages for which organoids main...
Interphase Cell Cycle Staging using Deep Learning.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2020
The progression of cells through the cell cycle is a tightly regulated process and is known to be key in maintaining normal tissue architecture and function. Disruption of these orchestrated phases will result in alterations that can lead to many dis...
Marsdeniae tenacissimae extract (MTE) suppresses cell proliferation by attenuating VEGF/VEGFR2 interactions and promotes apoptosis through regulating PKC pathway in human umbilical vein endothelial cells.
Chinese journal of natural medicines
Dec 1, 2016
Marsdeniae tenacissimae extract (MTE), commonly known as Xiao-Ai-Ping in China, is a traditional Chinese herb medicine capable of inhibiting proliferation and metastasis and boosting apoptosis in various cancer cells. However, little is known about t...
Effect of Fanbaicao (Herba Potentillae Discoloris) oil on the expression of p21 and CDK4 in HepG2 cells.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
Aug 1, 2016
OBJECTIVE: To research the anti-cancer mechanism of the Traditional Chinese Medicine Fanbaicao (Herba Potentillae Discoloris) oil in the human hepatoma cell line HepG2.
[Enhanced radiosensitivity of H22 ascitic tumor to 12C6+ ions radiation in ultra-filtration extract mixture from Astragalus mongholicus-treated mice].
Yao xue xue bao = Acta pharmaceutica Sinica
Dec 1, 2015
This study was designed to investigate the impact of ultra-filtration extract mixture from Astragals mongholicus (UEMAM) o radiosensitivity of H22 ascitic tumor in mice to 12C6+ ions radiation. The H22 ascitic tumor model was established in mice by i...
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