AIMC Topic: Microspheres

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Magnetically Driven Lasing Microrobots for Precise Photodynamic Therapy.

ACS nano
Photodynamic therapy (PDT) is an emerging approach for tumor treatment, valued for its noninvasive and stimuli-responsive properties. However, its therapeutic efficacy is often constrained by unintended damage to healthy tissues, largely due to the s...

Polymer microparticles in an evolving drug delivery landscape: challenges and the role of machine learning.

International journal of pharmaceutics
Polymer microparticles (MPs) have long been a cornerstone of long-acting injectable (LAI) drug delivery, offering controlled drug release, reduced dosing frequency, and improved patient adherence. Among these, poly(lactide-co-glycolide) (PLGA)-based ...

Dual-Stage Propulsion Strategy for Microalgae-Based Biohybrid Microrobots.

ACS applied materials & interfaces
Biohybrid microrobots, based on swimming microalgae, offer outstanding self-propulsion and functionalization capabilities, making them promising platforms for cargo loading and delivery. However, current technologies predominantly focus on in vitro n...

Artificial intelligence-enabled microsphere imaging immunosensor based on magnetic metal-organic frameworks-assisted sample pretreatment for detecting aflatoxin B in peanuts.

Journal of hazardous materials
Sensitive and rapid detection of aflatoxin B (AFB) is vital for safeguarding food safety, considering its potent carcinogenic toxicity. Herein, an artificial intelligence-enabled microsphere imaging (AI-MI) immunosensor based on magnetic metal-organi...

Deep-Learning-Assisted Microfluidic Immunoassay via Smartphone-Based Imaging Transcoding System for On-Site and Multiplexed Biosensing.

Nano letters
Point-of-care testing (POCT) with multiplexed capability, ultrahigh sensitivity, affordable smart devices, and user-friendly operation is critically needed for clinical diagnostics and food safety. This study presents a deep-learning-assisted microfl...

Enhanced Sensitivity and Versatile Detection: Dual-Sized Microsphere-Type Pressure Sensors for Soft Robotics and Wearable Electronics.

ACS applied materials & interfaces
The development of pressure sensors with enhanced sensitivity, expanded working range, and versatile yet decoupling detection capabilities is critical for advancing robotics and medical applications. This work presents a novel pressure sensor design ...

Deep Learning-Assisted Fluorescence Single-Particle Detection of Fumonisin B Powered by Entropy-Driven Catalysis and Argonaute.

Analytical chemistry
Timely and accurate detection of trace mycotoxins in agricultural products and food is significant for ensuring food safety and public health. Herein, a deep learning-assisted and entropy-driven catalysis (EDC)-Argonaute powered fluorescence single-p...

Kernel representation-based End-to-End network-enabled decoding strategy for precise and medical diagnosis.

Journal of hazardous materials
Artificial intelligence-assisted imaging biosensors have attracted increasing attention due to their flexibility, allowing for the digital image analysis and quantification of biomarkers. While deep learning methods have led to advancements in biomar...

Active Microrobots for Dual Removal of Biofilms via Chemical and Physical Mechanisms.

ACS applied materials & interfaces
Bacterial biofilms are complex multicellular communities that adhere firmly to solid surfaces. They are widely recognized as major threats to human health, contributing to issues such as persistent infections on medical implants and severe contaminat...

Size-Coded Hydrogel Microbeads for Extraction-Free Serum Multi-miRNAs Quantifications with Machine-Learning-Aided Lung Cancer Subtypes Classification.

Nano letters
Classifying lung cancer subtypes, which are characterized by multi-microRNAs (miRNAs) upregulation, is important for therapy and prognosis evaluation. Liquid biopsy is a promising approach, but the pretreatment of RNA extraction is labor-intensive an...