AMIA ... Annual Symposium proceedings. AMIA Symposium
Feb 10, 2017
Words which have different representations but are semantically related, such as dementia and delirium, can pose difficult issues in understanding text. We explore the use of interaction frequency data between semantic elements as a means to differen...
Reliable identification of near-native poses of docked protein-protein complexes is still an unsolved problem. The intrinsic heterogeneity of protein-protein interactions is challenging for traditional biophysical or knowledge based potentials and th...
Neural networks : the official journal of the International Neural Network Society
Jan 16, 2017
A suitable feature representation can faithfully preserve the intrinsic structure of data. However, traditional dimensionality reduction (DR) methods commonly use the original input features to define the intrinsic structure, which makes the estimate...
Neural networks : the official journal of the International Neural Network Society
Jan 12, 2017
Short text clustering is a challenging problem due to its sparseness of text representation. Here we propose a flexible Self-Taught Convolutional neural network framework for Short Text Clustering (dubbed STC), which can flexibly and successfully inc...
BACKGROUND: High-dimensional biomedical data are frequently clustered to identify subgroup structures pointing at distinct disease subtypes. It is crucial that the used cluster algorithm works correctly. However, by imposing a predefined shape on the...
Journal of integrative bioinformatics
Dec 22, 2016
The performance of many learning and data mining algorithms depends critically on suitable metrics to assess efficiency over the input space. Learning a suitable metric from examples may, therefore, be the key to successful application of these algor...
BACKGROUND: Monogeneans are flatworms (Platyhelminthes) that are primarily found on gills and skin of fishes. Monogenean parasites have attachment appendages at their haptoral regions that help them to move about the body surface and feed on skin and...
BACKGROUND: Regulation mechanisms between miRNAs and genes are complicated. To accomplish a biological function, a miRNA may regulate multiple target genes, and similarly a target gene may be regulated by multiple miRNAs. Wet-lab knowledge of co-regu...
Gene expression profiling followed by gene ontology (GO) term enrichment analysis can generate long lists of significant GO terms. To interpret these results and get biological insight in the data, filtering and rearranging these long lists of GO ter...
The Dishevelled/EGL-10/Pleckstrin (DEP) domain-containing (DEPDC) proteins have seven members. However, whether this superfamily can be distinguished from other proteins based only on the amino acid sequences, remains unknown. Here, we describe a com...