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Cochlea

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Effect of Transtympanic Injection of Melatonin on Cisplatin-Induced Ototoxicity.

The journal of international advanced otology
OBJECTIVE: Cisplatin is a chemotherapeutic agent that is widely used in cancer treatment. Numerous side effects have been detected, one of which is ototoxicity. Melatonin, a product of the pineal gland, has a neuroendocrinoimmunological role in verte...

High-accuracy drilling with an image guided light weight robot: autonomous versus intuitive feed control.

International journal of computer assisted radiology and surgery
PURPOSE: Assistance of robotic systems in the operating room promises higher accuracy and, hence, demanding surgical interventions become realisable (e.g. the direct cochlear access). Additionally, an intuitive user interface is crucial for the use o...

Predicting cochlear dead regions in patients with hearing loss through a machine learning-based approach: A preliminary study.

PloS one
We propose a machine learning (ML)-based model for predicting cochlear dead regions (DRs) in patients with hearing loss of various etiologies. Five hundred and fifty-five ears from 380 patients (3,770 test samples) diagnosed with sensorineural hearin...

Cellular cartography of the organ of Corti based on optical tissue clearing and machine learning.

eLife
The highly organized spatial arrangement of sensory hair cells in the organ of Corti is essential for inner ear function. Here, we report a new analytical pipeline, based on optical clearing of tissue, for the construction of a single-cell resolution...

Metal artifact reduction for the segmentation of the intra cochlear anatomy in CT images of the ear with 3D-conditional GANs.

Medical image analysis
Cochlear implants (CIs) are surgically implanted neural prosthetic devices that are used to treat severe-to-profound hearing loss. These devices are programmed post implantation and precise knowledge of the implant position with respect to the intra ...

Multi-Scale deep learning framework for cochlea localization, segmentation and analysis on clinical ultra-high-resolution CT images.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Performing patient-specific, pre-operative cochlea CT-based measurements could be helpful to positively affect the outcome of cochlear surgery in terms of intracochlear trauma and loss of residual hearing. Therefore, we prop...

Noise Exposure on Human Cochlea During Cochleostomy Formation Using Conventional and a Hand Guided Robotic Drill.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
OBJECTIVE: To investigate the disturbance induced in the cochlea during cochleostomy using conventional drill and a hand guided robotic drill.

[Preliminary application of robot-assisted electrode insertion in cochlear implantation].

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
To evaluate the safety and outcomes of robot-assisted electrode insertion in cochlear implantation. We first reported the case of robot-assisted electrode insertion of cochlear implantation in October 2019. A new slim electrode array of Nurotron co...