AIMC Topic: Colitis, Ulcerative
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Identifying Lactylation-related biomarkers and therapeutic drugs in ulcerative colitis: insights from machine learning and molecular docking.
BMC pharmacology & toxicology
May 13, 2025
BACKGROUND: Ulcerative colitis (UC), a chronic relapsing-remitting inflammatory bowel disease. Recent studies have shown that lactylation modifications may be involved in metabolic-immune interactions in intestinal inflammation through epigenetic reg...
Radiomics prediction of surgery in ulcerative colitis refractory to medical treatment.
Techniques in coloproctology
May 10, 2025
BACKGROUND: The surgeries in drug-resistant ulcerative colitis are determined by complex factors. This study evaluated the predictive performance of radiomics analysis on the basis of whether patients with ulcerative colitis in hospital were in the s...
Accurate, Robust, and Scalable Machine Abstraction of Mayo Endoscopic Subscores From Colonoscopy Reports.
Inflammatory bowel diseases
Mar 3, 2025
BACKGROUND: The Mayo endoscopic subscore (MES) is an important quantitative measure of disease activity in ulcerative colitis. Colonoscopy reports in routine clinical care usually characterize ulcerative colitis disease activity using free text descr...
Machine learning and metabolomics identify biomarkers associated with the disease extent of ulcerative colitis.
Journal of Crohn's & colitis
Feb 4, 2025
BACKGROUND AND AIMS: Ulcerative colitis (UC) is a metabolism-related chronic intestinal inflammatory disease. Disease extent is a key parameter of UC. Using serum metabolic profiling to identify noninvasive biomarkers of disease extent may inform the...
Combination of white-light imaging-based and narrow-band imaging-based artificial intelligence models during colonoscopy in patients with ulcerative colitis.
Journal of Crohn's & colitis
Jan 11, 2025
BACKGROUND AND AIMS: The long-term treat-to-target (T2T) approach in ulcerative colitis (UC) aims for endoscopic remission, but variability among endoscopists and a lack of precision in relapse prediction both limit its clinical usefulness. A recentl...
Artificial intelligence-enabled histology exhibits comparable accuracy to pathologists in assessing histological remission in ulcerative colitis: a systematic review, meta-analysis, and meta-regression.
Journal of Crohn's & colitis
Jan 11, 2025
BACKGROUND AND AIMS: Achieving histological remission is a desirable emerging treatment target in ulcerative colitis (UC), yet its assessment is challenging due to high inter- and intraobserver variability, reliance on experts, and lack of standardiz...
Ulcerative Colitis Severity Classification and Localized Extent (UC-SCALE): An Artificial Intelligence Scoring System for a Spatial Assessment of Disease Severity in Ulcerative Colitis.
Journal of Crohn's & colitis
Jan 11, 2025
BACKGROUND AND AIMS: Validated scoring methods such as the Mayo Clinic Endoscopic Subscore (MCES) evaluate ulcerative colitis (UC) severity at the worst colon segment, without considering disease extent. We present the Ulcerative Colitis Severity Cla...
Artificial Intelligence-assisted Video Colonoscopy for Disease Monitoring of Ulcerative Colitis: A Prospective Study.
Journal of Crohn's & colitis
Jan 11, 2025
BACKGROUNDS AND AIMS: The Mayo endoscopic subscore [MES] is the most popular endoscopic disease activity measure of ulcerative colitis [UC]. Artificial intelligence [AI]-assisted colonoscopy is expected to reduce diagnostic variability among endoscop...
Investigating the molecular mechanisms associated with ulcerative colitis through the application of single-cell combined spatial transcriptome sequencing.
Frontiers in immunology
Jan 1, 2025
BACKGROUND: Ulcerative colitis (UC) is a chronic inflammatory bowel disease marked by dysregulated immune responses, resulting in sustained inflammation and ulceration of the colonic and rectal mucosa. To elucidate the cellular subtypes and gene expr...
Global trends and hotspots of ulcerative colitis based on bibliometric and visual analysis from 1993 to 2022.
Medicine
Feb 2, 2024
Ulcerative colitis (UC) has seen a significant increase over the past 3 decades. However, our understanding of its etiology, pathogenesis, and pharmacological treatment remains limited. This comprehensive review aims to address these gaps by analyzin...
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