AIMC Topic: Colorectal Neoplasms

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The implementation of computer-aided detection in an initial endoscopy training improves the quality measures of trainees' future colonoscopies: a retrospective cohort study.

Surgical endoscopy
INTRODUCTION: The implementation of computer-aided detection (CADe) systems has resulted in a growing number of young endoscopists being trained using AI-enhanced devices. The potential impact of AI-enhanced training on the trainees' future performan...

Using a Multilingual AI Care Agent to Reduce Disparities in Colorectal Cancer Screening for Higher Fecal Immunochemical Test Adoption Among Spanish-Speaking Patients: Retrospective Analysis.

Journal of medical Internet research
BACKGROUND: Colorectal cancer (CRC) screening rates remain disproportionately low among Hispanic and Latino populations compared to non-Hispanic White populations. While artificial intelligence (AI) shows promise in health care delivery, concerns exi...

Predicting Early-Onset Colorectal Cancer in Individuals Below Screening Age Using Machine Learning and Real-World Data: Case Control Study.

JMIR cancer
BACKGROUND: Colorectal cancer is now the leading cause of cancer-related deaths among young Americans. Accurate early prediction and a thorough understanding of the risk factors for early-onset colorectal cancer (EOCRC) are vital for effective preven...

Deep learning based colorectal cancer detection in medical images: A comprehensive analysis of datasets, methods, and future directions.

Clinical imaging
This comprehensive review examines the current state and evolution of artificial intelligence applications in colorectal cancer detection through medical imaging from 2019 to 2025. The study presents a quantitative analysis of 110 high-quality public...

Integrated muti-omics data and machine learning reveal CD151 as a key biomarker inducing chemoresistance in metabolic syndrome-related early-onset left-sided colorectal cancer.

Functional & integrative genomics
Emerging evidence has suggested a potential pathological association between early-onset left-sided colorectal cancer (EOLCC) and metabolic syndrome (MetS). However, the underlying genetic and molecular mechanisms remain insufficiently elucidated. Th...

Neurodegeneration Promotes Tumorigenesis in Colorectal Cancer: Insights From Single-Cell and Spatial Multiomics.

JCO precision oncology
PURPOSE: Colorectal cancer (CRC) ranks third in global incidence and second in mortality, with rates increasing among younger populations. The enteric nervous system (ENS) is crucial for gastrointestinal function, and its dysfunction is associated wi...

Targeting INF2 with DiosMetin 7-O-β-D-Glucuronide: a new stratagem for colorectal cancer therapy.

BMC cancer
BACKGROUND AND PURPOSE: Colorectal cancer (CRC) is the third most prevalent malignancy in the gastrointestinal tract and the second leading cause of cancer-related deaths. Despite the identification of numerous biomarkers, their non-specific distribu...

Development and Validation of a Lifestyle-Based 10-Year Risk Prediction Model of Colorectal Cancer for Early Stratification: Evidence from a Longitudinal Screening Cohort in China.

Nutrients
Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide, with growing evidence linking risk to lifestyle and dietary factors. However, nutrition-related exposures have rarely been integrated into existing CRC ...

Dual-energy CT combined with histogram parameters in the assessment of perineural invasion in colorectal cancer.

International journal of colorectal disease
PURPOSE: The purpose is to evaluate the predictive value of dual-energy CT (DECT) combined with histogram parameters and a clinical prediction model for perineural invasion (PNI) in colorectal cancer (CRC).

Enhancing colorectal polyp segmentation with TCFMA-Net: A transformer-based cross feature and multi-attention network.

Artificial intelligence in medicine
To enhance polyp segmentation in colonoscopy images for early detection and diagnosis of colorectal cancer. The study proposed the Transformer-based cross feature multi-attention network (TCFMA-Net) for polyp segmentation by addressing challenges suc...