The GO-Cellular Component (GO-CC) ontology provides a controlled vocabulary for the consistent description of the subcellular compartments or macromolecular complexes where proteins may act. Current machine learning-based methods used for the automat...
A DNA-binding protein (DNA-BP) is a protein that can bind and interact with a DNA. Identification of DNA-BPs using experimental methods is expensive as well as time consuming. As such, fast and accurate computational methods are sought for predicting...
Predicting patients' risk of developing certain diseases is an important research topic in healthcare. Accurately identifying and ranking the similarity among patients based on their historical records is a key step in personalized healthcare. The el...
Automatic design of mechanical procedures solving abstract problems is a relevant scientific challenge. In particular, automatic design of membranes systems performing some prefixed tasks is an important and useful research topic in the area of Natur...
IEEE/ACM transactions on computational biology and bioinformatics
May 11, 2018
The important role of angiogenesis in cancer development has driven many researchers to investigate the prospects of noninvasive cancer diagnosis based on the technology of contrast-enhanced ultrasound (CEUS) imaging. This paper presents a deep learn...
BACKGROUND: In plants, long non-protein coding RNAs are believed to have essential roles in development and stress responses. However, relative to advances on discerning biological roles for long non-protein coding RNAs in animal systems, this RNA cl...
IEEE/ACM transactions on computational biology and bioinformatics
Apr 26, 2018
Control of gene regulatory networks (GRNs) to shift gene expression from undesirable states to desirable ones has received much attention in recent years. Most of the existing methods assume that the cost of intervention at each state and time point,...
Computational drug repositioning has been proven as a promising and efficient strategy for discovering new uses from existing drugs. To achieve this goal, a number of computational methods have been proposed, which are based on different data sources...
Journal of computational biology : a journal of computational molecular cell biology
Apr 25, 2018
Computational analysis of cellular appearance and its dynamics is used to investigate physiological properties of cells in biomedical research. In consideration of the great success of deep learning in video analysis, we first introduce two-stream co...
BACKGROUND: Finding potential drug targets is a crucial step in drug discovery and development. Recently, resources such as the Library of Integrated Network-Based Cellular Signatures (LINCS) L1000 database provide gene expression profiles induced by...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.