AIMC Topic: Computer Simulation

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Solving nonlinear equality constrained multiobjective optimization problems using neural networks.

IEEE transactions on neural networks and learning systems Jan 30, 2015
This paper develops a neural network architecture and a new processing method for solving in real time, the nonlinear equality constrained multiobjective optimization problem (NECMOP), where several nonlinear objective functions must be optimized in ...
Algorithms Humans Neural Networks, Computer Computer Simulation Pattern Recognition, Automated Nonlinear Dynamics Problem Solving
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Developmental time windows for axon growth influence neuronal network topology.

Biological cybernetics Jan 30, 2015
Early brain connectivity development consists of multiple stages: birth of neurons, their migration and the subsequent growth of axons and dendrites. Each stage occurs within a certain period of time depending on types of neurons and cortical layers....
Embryo, Nonmammalian Cell Division Caenorhabditis elegans Neurogenesis Time Models, Neurological Axons Synapses Computer Simulation Animals Neural Networks, Computer
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Structured patch model for a unified automatic and interactive segmentation framework.

Medical image analysis Jan 29, 2015
We present a novel interactive segmentation framework incorporating a priori knowledge learned from training data. The knowledge is learned as a structured patch model (StPM) comprising sets of corresponding local patch priors and their pairwise spat...
Algorithms Computer Simulation Reproducibility of Results Sensitivity and Specificity Models, Statistical Subtraction Technique Models, Biological Image Interpretation, Computer-Assisted Machine Learning Pattern Recognition, Automated Image Enhancement
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PARP activity in peripheral blood lymphocytes as a predictive biomarker for PARP inhibition in tumor tissues - A population pharmacokinetic/pharmacodynamic analysis of rucaparib.

Clinical pharmacology in drug development Jan 26, 2015
PURPOSE: Rucaparib is a potent Poly (ADP-ribose) Polymerase (PARP) inhibitor currently under clinical development. The objectives of this analysis were to establish population PK and PK/PD models for rucaparib, and to evaluate the predictability of P...
Models, Biological Computer Simulation Humans Drug Administration Schedule Lymphocytes Biomarkers Neoplasms Poly(ADP-ribose) Polymerases Indoles Infusions, Intravenous Poly(ADP-ribose) Polymerase Inhibitors
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A reduction for spiking integrate-and-fire network dynamics ranging from homogeneity to synchrony.

Journal of computational neuroscience Jan 21, 2015
In this paper we provide a general methodology for systematically reducing the dynamics of a class of integrate-and-fire networks down to an augmented 4-dimensional system of ordinary-differential-equations. The class of integrate-and-fire networks w...
Humans Neural Networks, Computer Neurons Computer Simulation Nonlinear Dynamics Models, Neurological Nerve Net Action Potentials
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An integrated breast cancer risk assessment and management model based on fuzzy cognitive maps.

Computer methods and programs in biomedicine Jan 21, 2015
BACKGROUND: There is a growing demand for women to be classified into different risk groups of developing breast cancer (BC). The focus of the reported work is on the development of an integrated risk prediction model using a two-level fuzzy cognitiv...
Neoplasm Grading Decision Support Techniques Expert Testimony Computer Simulation Mammography Female Risk Management Humans Algorithms Computational Biology Risk Factors Fuzzy Logic Breast Neoplasms Models, Statistical Risk Assessment
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Inference of other's internal neural models from active observation.

Bio Systems Jan 21, 2015
Recently, there have been several attempts to replicate theory of mind, which explains how humans infer the mental states of other people using multiple sensory input, with artificial systems. One example of this is a robot that observes the behavior...
Computer Simulation Robotics Observation Neural Networks, Computer Machine Learning Algorithms Physics Theory of Mind Humans
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Mode-Dependent Stochastic Synchronization for Markovian Coupled Neural Networks With Time-Varying Mode-Delays.

IEEE transactions on neural networks and learning systems Jan 20, 2015
This paper investigates the stochastic synchronization problem for Markovian hybrid coupled neural networks with interval time-varying mode-delays and random coupling strengths. The coupling strengths are mutually independent random variables and the...
Markov Chains Neural Networks, Computer Stochastic Processes Computer Simulation Time Factors
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Spontaneous motion on two-dimensional continuous attractors.

Neural computation Jan 20, 2015
Attractor models are simplified models used to describe the dynamics of firing rate profiles of a pool of neurons. The firing rate profile, or the neuronal activity, is thought to carry information. Continuous attractor neural networks (CANNs) descri...
Nerve Net Humans Action Potentials Neurons Neural Networks, Computer Nonlinear Dynamics Computer Simulation Models, Neurological
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Resilient Asynchronous H∞ Filtering for Markov Jump Neural Networks With Unideal Measurements and Multiplicative Noises.

IEEE transactions on cybernetics Jan 19, 2015
This paper is concerned with the resilient H∞ filtering problem for a class of discrete-time Markov jump neural networks (NNs) with time-varying delays, unideal measurements, and multiplicative noises. The transitions of NNs modes and desired mode-de...
Computer Simulation Models, Theoretical Markov Chains Neural Networks, Computer Stochastic Processes Cybernetics
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