AIMC Topic: Computer Simulation

Clear Filters Showing 3721 to 3730 of 4054 articles

A transformer architecture based on BERT and 2D convolutional neural network to identify DNA enhancers from sequence information.

Briefings in bioinformatics
Recently, language representation models have drawn a lot of attention in the natural language processing field due to their remarkable results. Among them, bidirectional encoder representations from transformers (BERT) has proven to be a simple, yet...

Anticancer peptides prediction with deep representation learning features.

Briefings in bioinformatics
Anticancer peptides constitute one of the most promising therapeutic agents for combating common human cancers. Using wet experiments to verify whether a peptide displays anticancer characteristics is time-consuming and costly. Hence, in this study, ...

An end-to-end heterogeneous graph representation learning-based framework for drug-target interaction prediction.

Briefings in bioinformatics
Accurately identifying potential drug-target interactions (DTIs) is a key step in drug discovery. Although many related experimental studies have been carried out for identifying DTIs in the past few decades, the biological experiment-based DTI ident...

Artificial intelligence-based predictions in neovascular age-related macular degeneration.

Current opinion in ophthalmology
PURPOSE OF REVIEW: Predicting treatment response and optimizing treatment regimen in patients with neovascular age-related macular degeneration (nAMD) remains challenging. Artificial intelligence-based tools have the potential to increase confidence ...

Applications of interpretability in deep learning models for ophthalmology.

Current opinion in ophthalmology
PURPOSE OF REVIEW: In this article, we introduce the concept of model interpretability, review its applications in deep learning models for clinical ophthalmology, and discuss its role in the integration of artificial intelligence in healthcare.

Bound2Learn: a machine learning approach for classification of DNA-bound proteins from single-molecule tracking experiments.

Nucleic acids research
DNA-bound proteins are essential elements for the maintenance, regulation, and use of the genome. The time they spend bound to DNA provides useful information on their stability within protein complexes and insight into the understanding of biologica...

On Neural Associative Memory Structures: Storage and Retrieval of Sequences in a Chain of Tournaments.

Neural computation
Associative memories enjoy many interesting properties in terms of error correction capabilities, robustness to noise, storage capacity, and retrieval performance, and their usage spans over a large set of applications. In this letter, we investigate...

Soft robotic steerable microcatheter for the endovascular treatment of cerebral disorders.

Science robotics
Catheters used for endovascular navigation in interventional procedures lack dexterity at the distal tip. Neurointerventionists, in particular, encounter challenges in up to 25% of aneurysm cases largely due to the inability to steer and navigate the...

Open set recognition algorithm based on Conditional Gaussian Encoder.

Mathematical biosciences and engineering : MBE
For the existing Closed Set Recognition (CSR) methods mistakenly identify unknown jamming signals as a known class, a Conditional Gaussian Encoder (CG-Encoder) for 1-dimensional signal Open Set Recognition (OSR) is designed. The network retains the o...

Single-particle diffusional fingerprinting: A machine-learning framework for quantitative analysis of heterogeneous diffusion.

Proceedings of the National Academy of Sciences of the United States of America
Single-particle tracking (SPT) is a key tool for quantitative analysis of dynamic biological processes and has provided unprecedented insights into a wide range of systems such as receptor localization, enzyme propulsion, bacteria motility, and drug ...