Frontiers in bioscience (Landmark edition)
Apr 24, 2025
BACKGROUND: mAm is a specific RNA modification that plays an important role in regulating mRNA stability, translational efficiency, and cellular stress response. mAm's precise identification is essential to gain insight into its functional mechanisms...
Studies in health technology and informatics
Apr 8, 2025
This paper introduces a novel approach for predicting symptom escalation in chemotherapy patients by leveraging Convolutional Neural Networks (CNNs). Accurate forecasting of symptom escalation is crucial in cancer care, as it enables timely intervent...
Sirtuins, a class of NAD+ -dependent deacetylases, play a key role in aging, metabolism, and longevity. Their interaction with NAD+ at the catalytic site is crucial for function, but experimental methods to map NAD+ binding sites are time consuming. ...
In post-translational modification, covalent bonds on lysine and attached chemical groups significantly change proteins' physical and chemical properties. They shape protein structures, enhance function and stability, and are vital for physiological ...
In post-genome-wide association study era, interpretation of noncoding variants remains a significant challenge due to their complexity and the limited understanding of their functions. Here, we developed MIRACN, a novel residual convolutional neural...
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
Feb 25, 2025
In order to realize the quantitative assessment of muscle strength in hand function rehabilitation and then formulate scientific and effective rehabilitation training strategies, this paper constructs a multi-scale convolutional neural network (MSCNN...
SUMMARY: Polygenic risk scores (PRSs) hold promise for early disease diagnosis and personalized treatment, but their overall discriminative power remains limited for many diseases in the general population. As a result, numerous novel PRS modeling te...
The international journal of medical robotics + computer assisted surgery : MRCAS
Feb 1, 2025
BACKGROUND: This research aims to use deep learning to create automated systems for better breast cancer detection and categorisation in mammogram images, helping medical professionals overcome challenges such as time consumption, feature extraction ...
The Journal of international medical research
Feb 1, 2025
OBJECTIVE: To study the classification performance of a pre-trained convolutional neural network (CNN) with transfer learning by artificial joint ultrasonography images in rheumatoid arthritis (RA).
Current diagnostic methods for dyslexia primarily rely on traditional paper-and-pencil tasks. Advanced technological approaches, including eye-tracking and artificial intelligence (AI), offer enhanced diagnostic capabilities. In this paper, we bridge...
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