AIMC Topic: COVID-19 Drug Treatment
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Identification of hospitalized mortality of patients with COVID-19 by machine learning models based on blood inflammatory cytokines.
Frontiers in public health
Nov 17, 2022
Coronavirus disease 2019 (COVID-19) spread worldwide and presented a significant threat to people's health. Inappropriate disease assessment and treatment strategies bring a heavy burden on healthcare systems. Our study aimed to construct predictive ...
DeepLPI: a novel deep learning-based model for protein-ligand interaction prediction for drug repurposing.
Scientific reports
Oct 28, 2022
The substantial cost of new drug research and development has consistently posed a huge burden for both pharmaceutical companies and patients. In order to lower the expenditure and development failure rate, repurposing existing and approved drugs by ...
Discovery of novel SARS-CoV-2 3CL protease covalent inhibitors using deep learning-based screen.
European journal of medicinal chemistry
Oct 3, 2022
SARS-CoV-2 3CL protease is one of the key targets for drug development against COVID-19. Most known SARS-CoV-2 3CL protease inhibitors act by covalently binding to the active site cysteine. Yet, computational screens against this enzyme were mainly f...
How has artificial intelligence impacted COVID-19 drug repurposing and what lessons have we learned?
Expert opinion on drug discovery
Sep 26, 2022
Prediction of Potential Commercially Available Inhibitors against SARS-CoV-2 by Multi-Task Deep Learning Model.
Biomolecules
Aug 21, 2022
The outbreak of COVID-19 caused millions of deaths worldwide, and the number of total infections is still rising. It is necessary to identify some potentially effective drugs that can be used to prevent the development of severe symptoms, or even dea...
The effectiveness of gabapentin and gabapentin/montelukast combination compared with dextromethorphan in the improvement of COVID-19- related cough: A randomized, controlled clinical trial.
The clinical respiratory journal
Jul 31, 2022
INTRODUCTION: Cough is one of the most common presenting symptoms of COVID-19, which can persist for weeks or months.
Artificial Intelligence Technologies for COVID-19 De Novo Drug Design.
International journal of molecular sciences
Mar 17, 2022
The recent covid crisis has provided important lessons for academia and industry regarding digital reorganization. Among the fascinating lessons from these times is the huge potential of data analytics and artificial intelligence. The crisis exponent...
COVID-19 IgG/IgM patterns, early IL-6 elevation and long-term radiological sequelae in 75 patients hospitalized due to interstitial pneumonia followed up from 3 to 12 months.
PloS one
Feb 22, 2022
BACKGROUND: COVID-19 pandemic resulted in about 165 million infections and 3.4 million deaths all over the world across 15 months. The most severe clinical presentation of COVID-19 diseases is interstitial pneumonia.
A Novel Deep Learning-Based Black Fungus Disease Identification Using Modified Hybrid Learning Methodology.
Contrast media & molecular imaging
Jan 27, 2022
Currently, countries across the world are suffering from a prominent viral infection called COVID-19. Most countries are still facing several issues due to this disease, which has resulted in several fatalities. The first COVID-19 wave caused devasta...
PRCTC: a machine learning model for prediction of response to corticosteroid therapy in COVID-19 patients.
Aging
Jan 12, 2022
Corticosteroid has been proved to be one of the few effective treatments for COVID-19 patients. However, not all the patients were suitable for corticosteroid therapy. In this study, we aimed to propose a machine learning model to forecast the respon...
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