AIMC Topic: Deep Learning

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scVAEDer: integrating deep diffusion models and variational autoencoders for single-cell transcriptomics analysis.

Genome biology Mar 21, 2025
Discovering a lower-dimensional embedding of single-cell data can improve downstream analysis. The embedding should encapsulate both the high-level features and low-level variations. While existing generative models attempt to learn such low-dimensio...
Autoencoder Deep Learning Single-Cell Analysis Humans Gene Expression Profiling Software Transcriptome
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Bulldogs stenosis degree classification using synthetic images created by generative artificial intelligence.

Scientific reports Mar 21, 2025
Nasal stenosis in bulldogs significantly impacts their quality of life, making early diagnosis crucial for effective treatment. This study developed an automated deep learning model to classify the severity of nasal stenosis using 1020 images of bull...
Dogs Dog Diseases Generative Artificial Intelligence Constriction, Pathologic Nasal Obstruction Neural Networks, Computer Artificial Intelligence Deep Learning Image Processing, Computer-Assisted Animals Humans
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RNAmigos2: accelerated structure-based RNA virtual screening with deep graph learning.

Nature communications Mar 21, 2025
RNAs are a vast reservoir of untapped drug targets. Structure-based virtual screening (VS) identifies candidate molecules by leveraging binding site information, traditionally using molecular docking simulations. However, docking struggles to scale w...
Deep Learning RNA Nucleic Acid Conformation Molecular Docking Simulation Binding Sites Riboswitch
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[Nobel Prize in physics 2024 : John J. Hopfield and Geoffrey E. Hinton. From Hopfield and Hinton to AlphaFold: The 2024 Nobel Prize honors the pioneers of deep learning].

Medecine sciences : M/S Mar 21, 2025
On October 8, 2024, the Nobel Prize in Physics was awarded to John J. Hopfield, professor at Princeton University, and Geoffrey E. Hinton, professor at the University of Toronto, for their "fundamental discoveries that made possible machine learning ...
Physics Nobel Prize History, 21st Century History, 20th Century Humans Deep Learning
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Artificial intelligence in chronic kidney disease management: a scoping review.

Theranostics Mar 21, 2025
Chronic kidney disease (CKD) is a major public health problem worldwide associated with cardiovascular disease, renal failure, and mortality. To effectively address this growing burden, innovative solutions to management are urgently required. We co...
Early Diagnosis Deep Learning Renal Insufficiency, Chronic Natural Language Processing Machine Learning Disease Management Humans Risk Assessment Artificial Intelligence
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Unveiling CNS cell morphology with deep learning: A gateway to anti-inflammatory compound screening.

PloS one Mar 21, 2025
Deciphering the complex relationships between cellular morphology and phenotypic manifestations is crucial for understanding cell behavior, particularly in the context of neuropathological states. Despite its importance, the application of advanced i...
Central Nervous System Animals Drug Evaluation, Preclinical Deep Learning Neurons Humans Image Processing, Computer-Assisted Neuroinflammatory Diseases Microglia Mice Anti-Inflammatory Agents
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Optimizing deep learning models for glaucoma screening with vision transformers for resource efficiency and the pie augmentation method.

PloS one Mar 21, 2025
Glaucoma is the leading cause of irreversible vision impairment, emphasizing the critical need for early detection. Typically, AI-based glaucoma screening relies on fundus imaging. To tackle the resource and time challenges in glaucoma screening with...
Neural Networks, Computer Glaucoma ROC Curve Deep Learning Humans
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Automated Detection of Microcracks Within Second Harmonic Generation Images of Cartilage Using Deep Learning.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society Mar 20, 2025
Articular cartilage, essential for smooth joint movement, can sustain micrometer-scale microcracks in its collagen network from low-energy impacts previously considered non-injurious. These microcracks may propagate under cyclic loading, impairing ca...
Deep Learning Humans Cartilage, Articular Second Harmonic Generation Microscopy Animals
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An extragradient and noise-tuning adaptive iterative network for diffusion MRI-based microstructural estimation.

Medical image analysis Mar 20, 2025
Diffusion MRI (dMRI) is a powerful technique for investigating tissue microstructure properties. However, advanced dMRI models are typically complex and nonlinear, requiring a large number of acquisitions in the q-space. Deep learning techniques, spe...
Humans Diffusion Magnetic Resonance Imaging Deep Learning Algorithms Image Processing, Computer-Assisted Brain
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Enhancing skin disease classification leveraging transformer-based deep learning architectures and explainable AI.

Computers in biology and medicine Mar 20, 2025
Skin diseases affect over a third of the global population, yet their impact is often underestimated. Automating the classification of these diseases is essential for supporting timely and accurate diagnoses. This study leverages Vision Transformers,...
Databases, Factual Deep Learning Skin Diseases Humans Neural Networks, Computer
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