AIMC Topic: Deep Learning

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Deep learning allows genome-scale prediction of Michaelis constants from structural features.

PLoS biology
The Michaelis constant KM describes the affinity of an enzyme for a specific substrate and is a central parameter in studies of enzyme kinetics and cellular physiology. As measurements of KM are often difficult and time-consuming, experimental estima...

Evaluation Technology of Classroom Students' Learning State Based on Deep Learning.

Computational intelligence and neuroscience
Facial features are an effective representation of students' fatigue state, and the eye is more closely related to fatigue state. However, there are three main problems in the existing research: (1) the positioning of the eye is vulnerable to the ext...

Classification of Arrhythmia in Heartbeat Detection Using Deep Learning.

Computational intelligence and neuroscience
The electrocardiogram (ECG) is one of the most widely used diagnostic instruments in medicine and healthcare. Deep learning methods have shown promise in healthcare prediction challenges involving ECG data. This paper aims to apply deep learning tech...

Should we replace radiologists with deep learning? Pigeons, error and trust in medical AI.

Bioethics
The sudden rise in the ability of machine learning methodology, such as deep neural networks, to identify and predict with great accuracy instances of malignant cell growth from radiological images has led prominent developers of this technology, suc...

Image-based deep learning reveals the responses of human motor neurons to stress and VCP-related ALS.

Neuropathology and applied neurobiology
AIMS: Although morphological attributes of cells and their substructures are recognised readouts of physiological or pathophysiological states, these have been relatively understudied in amyotrophic lateral sclerosis (ALS) research.

Radon potential mapping in Jangsu-gun, South Korea using probabilistic and deep learning algorithms.

Environmental pollution (Barking, Essex : 1987)
The adverse health effects associated with the inhalation and ingestion of naturally occurring radon gas produced during the uranium decay chain mean that there is a need to identify high-risk areas. This study detected radon-prone areas using a geog...

Few-shot learning for deformable image registration in 4DCT images.

The British journal of radiology
OBJECTIVES: To develop a rapid and accurate 4D deformable image registration (DIR) approach for online adaptive radiotherapy.

Effective prediction of heart disease using hybrid ensemble deep learning and tunicate swarm algorithm.

Journal of biomolecular structure & dynamics
Heart disease (HD) is the major reason for the rampant cause of death around the world. It is deemed as a crucial illness among the middle and old age people which tends to high mortality rates. Recently, Effects of HD is presenting a shocking rise i...

Application of Deep Neural Network Models in Drug Discovery Programs.

ChemMedChem
In silico driven optimization of compound properties related to pharmacokinetics, pharmacodynamics, and safety is a key requirement in modern drug discovery. Nowadays, large and harmonized datasets allow to implement deep neural networks (DNNs) as a ...

3D-Scaffold: A Deep Learning Framework to Generate 3D Coordinates of Drug-like Molecules with Desired Scaffolds.

The journal of physical chemistry. B
The prerequisite of therapeutic drug design and discovery is to identify novel molecules and developing lead candidates with desired biophysical and biochemical properties. Deep generative models have demonstrated their ability to find such molecules...