AIMC Topic: Exhalation

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Exhaled gas biomarkers: a non-invasive approach for distinguishing diabetes and its complications.

The Analyst
Exhaled gas detection offers a safe, convenient, and non-invasive clinical diagnostic method for preventing the progression of diabetes to complications. In this study, gas chromatography-mass spectrometry (GC-MS) analysis and statistical methods wer...

Determination of lung cancer exhaled breath biomarkers using machine learning-a new analysis framework.

Scientific reports
Exhaled breath samples of lung cancer patients (LC), tuberculosis (TB) patients and asymptomatic controls (C) were analyzed using gas chromatography-mass spectrometry (GC-MS). Ten volatile organic compounds (VOCs) were identified as possible biomarke...

Assessing chronic obstructive pulmonary disease risk based on exhalation and cough sounds.

Biomedical engineering online
BACKGROUND AND OBJECTIVE: Chronic obstructive pulmonary disease (COPD), a progressively worsening respiratory condition, severely impacts patient quality of life. Early risk assessment can improve treatment outcomes and lessen healthcare burdens. How...

Breath profiles in paediatric allergic asthma by proton transfer reaction mass spectrometry.

BMJ open respiratory research
INTRODUCTION: Enhancing paediatric asthma diagnosis is crucial. Molecular analysis of exhaled breath is a rapidly evolving field aimed at harnessing established and innovative technologies for clinical applications. This study evaluates the feasibili...

Considerations regarding the selection, sampling, extraction, analysis, and modelling of biomarkers in exhaled breath for early lung cancer screening.

Journal of pharmaceutical and biomedical analysis
Lung cancer (LC) is the deadliest cancer due to the lack of efficient screening methods that detect the disease early. This review, covering the years 2011 - 2025, summarizes state-of-the-art LC screening through analysis of volatile organic compound...

Detection of Breath Nitric Oxide at Ppb Level Based on Multiperiodic Spectral Reconstruction Neural Network.

Analytical chemistry
As breath nitric oxide (NO) is a biomarker of respiratory inflammation, reliable techniques for the online detection of ppb-level NO in exhaled breath are essential for the noninvasive diagnosis of respiratory inflammation. Here, we report a breath N...

Noninvasive Total Cholesterol Level Measurement Using an E-Nose System and Machine Learning on Exhaled Breath Samples.

ACS sensors
In this paper, the first e-nose system coupled with machine learning algorithm for noninvasive measurement of total cholesterol level based on exhaled air sample was proposed. The study was conducted with the participation of 151 people, from whom a ...

BreathVisionNet: A pulmonary-function-guided CNN-transformer hybrid model for expiratory CT image synthesis.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Chronic obstructive pulmonary disease (COPD) has high heterogeneity in etiologies and clinical manifestations. Expiratory Computed tomography (CT) can effectively assess air trapping, aiding in disease diagnosis. However, du...

Deep-Learning-Based Blood Glucose Detection Device Using Acetone Exhaled Breath Sensing Features of α-FeO-MWCNT Nanocomposites.

ACS applied materials & interfaces
Owing to the correlation between acetone in human's exhaled breath (EB) and blood glucose, the development of EB acetone gas-sensing devices is important for early diagnosis of diabetes diseases. In this article, a noninvasive blood glucose detection...

Ppb-Level Ammonia Sensor for Exhaled Breath Diagnosis Based on UV-DOAS Combined with Spectral Reconstruction Fitting Neural Network.

ACS sensors
Ammonia (NH) in exhaled breath (EB) has been a biomarker for kidney function, and accurate measurement of NH is essential for early screening of kidney disease. In this work, we report an optical sensor that combines ultraviolet differential optical ...