The key finding in the DNA double helix model is the specific pairing or binding between nucleotides A-T and C-G, and the pairing rules are the molecule basis of genetic code. Unfortunately, no such rules have been discovered for proteins. Here we sh...
The hippocampus places us both in time and space. It does so over remarkably large spans: milliseconds to years, and centimeters to kilometers. This works for sensory representations, for memory, and for behavioral context. How does it fit in such wi...
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Oct 30, 2017
Accurate quantification of uptake on PET images depends on accurate attenuation correction in reconstruction. Current MR-based attenuation correction methods for body PET use a fat and water map derived from a 2-echo Dixon MRI sequence in which bone ...
IEEE journal of biomedical and health informatics
Oct 27, 2017
The past decade has seen an explosion in the amount of digital information stored in electronic health records (EHRs). While primarily designed for archiving patient information and performing administrative healthcare tasks like billing, many resear...
IEEE transactions on neural networks and learning systems
Oct 25, 2017
In a real brain, the act of perception is a bidirectional process, depending on both feedforward sensory pathways and feedback pathways that carry expectations. We are interested in how such a neural network might emerge from a biologically plausible...
BACKGROUND: In general, academic but not community endoscopists have demonstrated adequate endoscopic differentiation accuracy to make the 'resect and discard' paradigm for diminutive colorectal polyps workable. Computer analysis of video could poten...
Computer assisted surgery (Abingdon, England)
Oct 18, 2017
Malignant melanoma is one of the most deadly forms of skin cancer, which is one of the world's fastest-growing cancers. Early diagnosis and treatment is critical. In this study, a neural network structure is utilized to construct a broad and accurate...
IEEE/ACM transactions on computational biology and bioinformatics
Oct 9, 2017
Prediction of the spatial structure or function of biological macromolecules based on their sequences remains an important challenge in bioinformatics. When modeling biological sequences using traditional sequencing models, long-range interaction, co...
Clinical cancer research : an official journal of the American Association for Cancer Research
Oct 5, 2017
Identifying robust survival subgroups of hepatocellular carcinoma (HCC) will significantly improve patient care. Currently, endeavor of integrating multi-omics data to explicitly predict HCC survival from multiple patient cohorts is lacking. To fill ...
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