OBJECTIVE: Our study aims to develop a deep learning-based Ankylosing Spondylitis (AS) diagnostic model that achieves human expert-level performance using only a minimal amount of labeled samples for training, in regions with limited access to expert...
Globular proteins (GPs) play vital roles in a wide range of biological processes, encompassing enzymatic catalysis and immune responses. Enzymes, among these globular proteins, facilitate biochemical reactions, while others, such as haemoglobin, cont...
Proceedings of the National Academy of Sciences of the United States of America
Nov 8, 2024
Cellular deconvolution via bulk RNA sequencing (RNA-seq) presents a cost-effective and efficient alternative to experimental methods such as flow cytometry and single-cell RNA-seq (scRNA-seq) for analyzing the complex cellular composition of tumor mi...
BACKGROUND: Patients with partial anomalous pulmonary venous connection (PAPVC) usually present asymptomatic and accompanied by intricate anatomical types, which results in missed diagnosis from atrial septal defect (ASD). The present study aimed to ...
Fluorescence in Situ Hybridization (FISH) is a technique for macromolecule identification that utilizes the complementarity of DNA or DNA/RNA double strands. Probes, crafted from selected DNA strands tagged with fluorophore-coupled nucleotides, hybri...
Automated blood vessel segmentation is critical for biomedical image analysis, as vessel morphology changes are associated with numerous pathologies. Still, precise segmentation is difficult due to the complexity of vascular structures, anatomical va...
Deep generative models are gaining attention in the field of de novo drug design. However, the rational design of ligand molecules for novel targets remains challenging, particularly in controlling the properties of the generated molecules. Here, ins...
Autism is a developmental disability. Research demonstrated that children with autism benefit from early diagnosis and early intervention. Genetic factors are considered major contributors to the development of autism. Machine learning (ML), includin...
The brain is a crucial organ that controls the body's neural system. The tumor develops and spreads across the brain as a result of irregular cell generation. The provision of substantial treatment to patients requires the early diagnosis of malignan...
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