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Spondylitis, Ankylosing

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Rapid screening for autoimmune diseases using Fourier transform infrared spectroscopy and deep learning algorithms.

Frontiers in immunology
INTRODUCE: Ankylosing spondylitis (AS), rheumatoid arthritis (RA), and osteoarthritis (OA) are three rheumatic immune diseases with many common characteristics. If left untreated, they can lead to joint destruction and functional limitation, and in s...

Comprehensive AI-assisted tool for ankylosing spondylitis based on multicenter research outperforms human experts.

Frontiers in public health
INTRODUCTION: The diagnosis and treatment of ankylosing spondylitis (AS) is a difficult task, especially in less developed countries without access to experts. To address this issue, a comprehensive artificial intelligence (AI) tool was created to he...

Rapid diagnosis of rheumatoid arthritis and ankylosing spondylitis based on Fourier transform infrared spectroscopy and deep learning.

Photodiagnosis and photodynamic therapy
OBJECTIVE: Rheumatoid arthritis and Ankylosing spondylitis are two common autoimmune inflammatory rheumatic diseases that negatively affect activities of daily living and can lead to structural and functional disability, reduced quality of life. Here...

Radiomics-based machine learning model to phenotype hip involvement in ankylosing spondylitis: a pilot study.

Frontiers in immunology
OBJECTIVES: Hip involvement is an important reason of disability in patients with ankylosing spondylitis (AS). Unveiling the potential phenotype of hip involvement in AS remains an unmet need to understand its biological mechanisms and improve clinic...

Clinical Outcome Analysis of Robot-Assisted Pedicle Screw Insertion in the Treatment of Ankylosing Spondylitis Complicated with Spinal Fractures.

World neurosurgery
BACKGROUND: Vague spinal anatomical landmarks in patients with ankylosing spondylitis (AS) make intraoperative insertion of pedicle screws difficult under direct vision. Currently, the clinical outcome is significantly improved with robot guidance. T...

Sex dimorphism of IL-17-secreting peripheral blood mononuclear cells in ankylosing spondylitis based on bioinformatics analysis and machine learning.

BMC musculoskeletal disorders
BACKGROUND: Ankylosing spondylitis (AS) with radiographic damage is more prevalent in men than in women. IL-17, which is mainly secreted from peripheral blood mononuclear cells (PBMCs), plays an important role in the development of AS. Its expression...

A novel semi-supervised learning model based on pelvic radiographs for ankylosing spondylitis diagnosis reduces 90% of annotation cost.

Computers in biology and medicine
OBJECTIVE: Our study aims to develop a deep learning-based Ankylosing Spondylitis (AS) diagnostic model that achieves human expert-level performance using only a minimal amount of labeled samples for training, in regions with limited access to expert...

A machine learning approach for the design optimization of a multiple magnetic and inertial sensors wearable system for the spine mobility assessment.

Journal of neuroengineering and rehabilitation
BACKGROUND: Recently, magnetic and inertial measurement units (MIMU) based systems have been applied in the spine mobility assessment; this evaluation is essential in the clinical practice for diagnosis and treatment evaluation. The available systems...

Development and validation of machine learning algorithms for early detection of ankylosing spondylitis using magnetic resonance images.

Technology and health care : official journal of the European Society for Engineering and Medicine
BackgroundAnkylosing spondylitis (AS) is a chronic inflammatory disease affecting the sacroiliac joints and spine, often leading to disability if not diagnosed and treated early.ObjectiveIn this study, we present the development and validation of mac...

Oxidative Phosphorylation Pathway in Ankylosing Spondylitis: Multi-Omics Analysis and Machine Learning.

International journal of rheumatic diseases
INTRODUCTION: Ankylosing spondylitis (AS) is a chronic inflammatory disease affecting the axial skeleton, characterized by immune microenvironment dysregulation and elevated cytokines like TNF-α and IL-17. Mitochondrial oxidative phosphorylation (OXP...