The gut-bone axis is pivotal in the pathogenesis of ankylosing spondylitis (AS), with gut dysbiosis and mucosal immune activation driving skeletal pathology. However, translating these mechanistic insights into effective therapies remains challenging...
BACKGROUND: Ankylosing spondylitis (AS), a chronic inflammatory disorder affecting axial joints, is frequently complicated by uveitis. However, the molecular mechanisms linking AS to secondary uveitis remain poorly understood.
Ankylosing spondylitis (AS) and rheumatoid arthritis (RA) are closely related autoimmune diseases with shared mechanisms that remain unclear. This study aims to identify shared molecular signatures and hub genes underlying the co-occurrence of AS and...
Ankylosing Spondylitis (AS), commonly known as Bechterew's disease, is a complex, potentially disabling disease that develops slowly over time and progresses to radiographic sacroiliitis. The etiology of this disease is poorly understood, making it d...
Ankylosing spondylitis (AS), which usually occurs in the second and third decades of life, is associated with chronic pain, limitation of mobility, and severe decreases in quality of life. This study aimed to make a comparative evaluation in terms of...
BACKGROUND: The development of the Artificial Intelligence (AI)-based severity inspection model for ankylosing spondylitis (AS) could support health professionals to rapidly assess the severity of the disease, enhance proficiency, and reduce the dema...
Ankylosing spondylitis (AS) is linked to an increased prevalence of myocardial infarction (MI). However, research dedicated to elucidating the pathogenesis of AS-MI is lacking. In this study, we explored the biomarkers for enhancing the diagnostic an...
Technology and health care : official journal of the European Society for Engineering and Medicine
Dec 29, 2024
BackgroundAnkylosing spondylitis (AS) is a chronic inflammatory disease affecting the sacroiliac joints and spine, often leading to disability if not diagnosed and treated early.ObjectiveIn this study, we present the development and validation of mac...
OBJECTIVE: Our study aims to develop a deep learning-based Ankylosing Spondylitis (AS) diagnostic model that achieves human expert-level performance using only a minimal amount of labeled samples for training, in regions with limited access to expert...
Journal of neuroengineering and rehabilitation
Nov 5, 2024
BACKGROUND: Recently, magnetic and inertial measurement units (MIMU) based systems have been applied in the spine mobility assessment; this evaluation is essential in the clinical practice for diagnosis and treatment evaluation. The available systems...
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