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Depressive Disorder, Major

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Seeking for potential pathogenic genes of major depressive disorder in the Gene Expression Omnibus database.

Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists
INTRODUCTION: Major depressive disorder (MDD) is one of the most common mental disorders worldwide. The aim of this study was to identify potential pathological genes in MDD.

Ensemble Learning for Early-Response Prediction of Antidepressant Treatment in Major Depressive Disorder.

Journal of magnetic resonance imaging : JMRI
BACKGROUND: In order to reduce unsuccessful treatment trials for depression, neuroimaging and genetic information can be considered as biomarkers. Together with machine-learning methods, prediction models have proved to be valuable for baseline predi...

Classification of Depression Patients and Normal Subjects Based on Electroencephalogram (EEG) Signal Using Alpha Power and Theta Asymmetry.

Journal of medical systems
Depression or Major Depressive Disorder (MDD) is a mental illness which negatively affects how a person thinks, acts or feels. MDD has become a major disease affecting millions of people presently. The diagnosis of depression is questionnaire based a...

Predicting rehospitalization within 2 years of initial patient admission for a major depressive episode: a multimodal machine learning approach.

Translational psychiatry
Machine learning methods show promise to translate univariate biomarker findings into clinically useful multivariate decision support systems. At current, works in major depressive disorder have predominantly focused on neuroimaging and clinical pred...

ARPNet: Antidepressant Response Prediction Network for Major Depressive Disorder.

Genes
Treating patients with major depressive disorder is challenging because it takes several months for antidepressants prescribed for the patients to take effect. This limitation may result in increased risks and treatment costs. To address this limitat...

A network perspective on body dysmorphic disorder and major depressive disorder.

Journal of affective disorders
BACKGROUND: Body dysmorphic disorder (BDD) is a highly debilitating mental disorder associated with notable psychosocial impairment and high rates of suicidality. This study investigated BDD from a network perspective, which conceptualizes mental dis...

Resting-State Functional Network Scale Effects and Statistical Significance-Based Feature Selection in Machine Learning Classification.

Computational and mathematical methods in medicine
In recent years, functional brain network topological features have been widely used as classification features. Previous studies have found that network node scale differences caused by different network parcellation definitions significantly affect...

Machine Learning Identifies Large-Scale Reward-Related Activity Modulated by Dopaminergic Enhancement in Major Depression.

Biological psychiatry. Cognitive neuroscience and neuroimaging
BACKGROUND: Theoretical models have emphasized systems-level abnormalities in major depressive disorder (MDD). For unbiased yet rigorous evaluations of pathophysiological mechanisms underlying MDD, it is critically important to develop data-driven ap...

Improving documentation of presenting problems in the emergency department using a domain-specific ontology and machine learning-driven user interfaces.

International journal of medical informatics
OBJECTIVES: To determine the effect of a domain-specific ontology and machine learning-driven user interfaces on the efficiency and quality of documentation of presenting problems (chief complaints) in the emergency department (ED).