AIMC Topic: Diabetes Mellitus, Experimental

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Two-way learning with one-way supervision for gene expression data.

BMC bioinformatics
BACKGROUND: A family of parsimonious Gaussian mixture models for the biclustering of gene expression data is introduced. Biclustering is accommodated by adopting a mixture of factor analyzers model with a binary, row-stochastic factor loadings matrix...

BOLA3 as a key protein for the treatment of diabetic skeletal muscle atrophy.

International immunopharmacology
OBJECTIVE: Skeletal muscle is crucial for glucose metabolism, but diabetes impairs this function, leading to muscle atrophy. Although the mutation of BOLA Family Member 3 (BOLA3) resulted in disease Multiple Mitochondrial Dysfunctions Syndrome, the r...

Integration of multi-omics data and machine learning to identify antioxidant biomarkers in type 1 diabetes.

Free radical biology & medicine
The identification of biomarkers for early diagnosis and monitoring the progression of Type 1 Diabetes (T1DM) is essential for improving disease management. This study integrates multi-omics data with machine learning to identify antioxidant stress p...

Exploration of hypoglycemic effect of an extract from leaves of a plant from Tunisian pharmacopeia: ().

African health sciences
BACKGROUND AND OBJECTIVES: A lot of research has been directed towards medicinal plants which are considered as a source of multiple phytotherapic substances endowed with hypoglycemic activities that could be used to treat diabetes and its complicati...

[rhPDGF-BB promotes migration of bone marrow stromal stem cells in diabetic rats].

Shanghai kou qiang yi xue = Shanghai journal of stomatology
PURPOSE: To evaluate the effect of different concentrations of rhPDGF-BB on bone marrow stromal stem cells(BMSCs) migration in diabetic rat, and related mechanisms of SDF-1 and its G-protein conjugated receptor regulation, provide a theoretical basis...