AIMC Topic: Drugs, Chinese Herbal

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Traditional Chinese Medicine for Anti-Arrhythmias: Mechanisms via Potassium Channels.

Basic & clinical pharmacology & toxicology
Cardiac arrhythmia is a common life-threatening cardiovascular disorder. Potassium channels play a crucial role in cardiac electrophysiology, and their dysfunction is closely associated with the occurrence and development of arrhythmia. Traditional C...

Hugan Tiaoshen Formula Improves the Comorbid Mechanism of Schizophrenia and Sleep Disorder via Multitarget Interaction Network.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
This study aims to integrate cross-disease omics data and perform multidimensional analysis to uncover the molecular basis of schizophrenia (SCZ) and sleep disorder (SD) comorbidity and to systematically analyze the potential mechanism of the Hugan T...

Machine learning and chemometric methods for high-throughput authentication of 53 Root and Rhizome Chinese Herbal using ATR-FTIR fingerprints.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
To address the identification challenges caused by morphological similarities in Root and Rhizome Chinese Herbal (RRCH), this study developed a discrimination system integrating Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy (AT...

A prognostic model of immunoglobulin A nephropathy using artificial neural network: a retrospective study based on integrated Chinese and Western Medicine.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
OBJECTIVE: To establish and evaluate a prognostic model of immunoglobulin A nephropathy (IgAN) based on integrated Chinese and Western Medicine.

Altered cerebral functional activity and its associated genetic profiles underlying chronic insomnia disorder before and after treatment.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
OBJECTIVES: The resting-state cerebral functional activity underlying chronic insomnia disorder (CID) remains inconsistent, and the effects of pharmacotherapy on such activity are unclear.

Alpha test 1 robotic platform for traditional Chinese medicine pretreatment: Automated modular integration and quality control applications.

SLAS technology
Sample pretreatment plays an important role in analytical performance, but it is often the rate-limiting step in scientific research. With the development of automation technology, automated sample preparation has become a powerful tool for liberatin...

Utilizing semantically enhanced self-supervised graph convolution and multi-head attention fusion for herb recommendation.

Artificial intelligence in medicine
Traditional Chinese herbal medicine has long been recognized as an effective natural therapy. Recently, the development of recommendation systems for herbs has garnered widespread academic attention, as these systems significantly impact the applicat...

Exploration of Active Substances and Its Potential Mechanism of Gancao Fuzi Decoction on Inflammatory Based on Metabolomics and Network Pharmacology.

Rapid communications in mass spectrometry : RCM
Gancao Fuzi decoction (GCFZT) is a traditional Chinese formula, which has been commonly used in clinical practice to treat inflammatory diseases. However, the active substance of GCFZT in the treatment of inflammation is not fully clarified. In this ...

Integrating machine learning and traditional methods for cadmium prediction and bioavailability assessment in Paeoniae Radix Alba: a case study from Bozhou, Anhui Province.

Environmental geochemistry and health
Soil heavy metal contamination, particularly cadmium (Cd), poses a significant risk to ecosystems and human health. This study investigates the distribution and bioavailability of Cd in soil and Paeoniae Radix Alba system from Qiaocheng District, Boz...

Boi-Ogi-To, a Traditional Japanese Kampo Medicine, Promotes Cellular Excretion of Chloride and Water by Activating Volume-Sensitive Outwardly Rectifying Anion Channels.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
The Japanese Kampo medicine Boi-ogi-to (BOT) is known as an effective therapeutic agent for edema and nephrosis by promoting the excretion of excess body fluids. Despite its empirical effectiveness, scientific evidence supporting its effectiveness re...