AIMC Topic: Flow Cytometry

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Toxicity of titanium dioxide nanoparticles on Pseudomonas putida.

Water research
The increasing use of engineered nanoparticles (NPs) in industrial and household applications will very likely lead to the release of such materials into the environment. As wastewater treatment plants (WWTPs) are usually the last barrier before the ...

Label-free and dynamic evaluation of cell-surface epidermal growth factor receptor expression via an electrochemiluminescence cytosensor.

Talanta
A label-free electrochemiluminescence (ECL) cytosensor was developed for dynamically evaluating of epidermal growth factor receptor (EGFR) expression on MCF-7 cancer cells based on the specific recognition of epidermal growth factor (EGF) with its re...

Methods for discovery and characterization of cell subsets in high dimensional mass cytometry data.

Methods (San Diego, Calif.)
The flood of high-dimensional data resulting from mass cytometry experiments that measure more than 40 features of individual cells has stimulated creation of new single cell computational biology tools. These tools draw on advances in the field of m...

flowCL: ontology-based cell population labelling in flow cytometry.

Bioinformatics (Oxford, England)
MOTIVATION: Finding one or more cell populations of interest, such as those correlating to a specific disease, is critical when analysing flow cytometry data. However, labelling of cell populations is not well defined, making it difficult to integrat...

Artificial intelligence accelerates the interpretation of measurable residual B lymphoblastic leukemia by flow cytometry.

Blood advances
Measurable residual disease (MRD) assessment by flow cytometry (FC) plays an essential role in prognosis and therapy escalation of B-cell acute lymphoblastic leukemia (B-ALL). However, the high degree of expertise and manual analysis time required li...

A machine learning approach to risk-stratification of gastric cancer based on tumour-infiltrating immune cell profiles.

Annals of medicine
BACKGROUND: Gastric cancer (GC) is a highly heterogeneous disease, and the response of patients to clinical treatment varies substantially. There is no satisfactory strategy for predicting curative effects to date. We aimed to explore a new method fo...

Artificial intelligence-based flow cytometry for the diagnosis of B-cell chronic lymphoproliferative disorders.

Blood advances
Accurate diagnosis of B-cell chronic lymphoproliferative disorders (B-CLPDs) remains challenging due to overlapping phenotypes across subtypes. Machine learning (ML) offers promising tools to improve marker evaluation and refine flow cytometry analys...

A machine learning framework for cross-institute standardized analysis of flow cytometry in differentiating acute myeloid leukemia from non-neoplastic conditions.

Computers in biology and medicine
Flow cytometry (FC) remains a cornerstone diagnostic tool for acute myeloid leukemia (AML), yet standardizing panels across laboratories presents persistent challenges. Our study introduces a validated machine learning framework enabling cross-panel ...

Characterization of unique pattern of immune cell profile in patients with nasopharyngeal carcinoma through flow cytometry and machine learning.

Journal of cellular and molecular medicine
In patients with nasopharyngeal carcinoma (NPC), the alteration of immune responses in peripheral blood remains unclear. In this study, we established an immune cell profile for patients with NPC and used flow cytometry and machine learning (ML) to i...

Surrogate gradient learning in spiking networks trained on event-based cytometry dataset.

Optics express
Spiking neural networks (SNNs) are bio-inspired neural networks that - to an extent - mimic the workings of our brains. In a similar fashion, event-based vision sensors try to replicate a biological eye as closely as possible. In this work, we integr...