AIMC Topic: Fluorocarbons

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Maternal serum concentrations of perfluoroalkyl acids in five international birth cohorts.

International journal of hygiene and environmental health
BACKGROUND: Perfluoroalkyl acids (PFAAs) are persistent and bioaccumulating compounds, which are spread all over the globe. We aimed to compare the PFAA concentrations in serum from pregnant women in five birth cohorts from four countries (Denmark, C...

Determination of selected synthetic cannabinoids and their metabolites by micellar electrokinetic chromatography--mass spectrometry employing perfluoroheptanoic acid-based micellar phase.

Talanta
Perfluoroheptanoic acid was employed as a volatile micellar phase in background electrolyte for micellar electrokinetic chromatography-tandem mass spectrometry separation and determination of 15 selected naphthoyl- and phenylacetylindole- synthetic c...

Perfluorooctanoic acid-induced toxicity in primary cultures of chicken embryo cardiomyocytes.

Environmental toxicology
Perfluorooctanoic acid (PFOA) is a widespread environmental contaminant that induces developmental cardiotoxicity. It is detectable in late stage chicken embryos and hatchling chickens. To investigate mechanism(s) of cardiotoxicity, primary cultures ...

An automated high-throughput SPE micro-elution method for perfluoroalkyl substances in human serum.

Analytical and bioanalytical chemistry
An automated high-throughput solid phase extraction (SPE) micro-elution method for 8 perfluorosulfonic acids, 11 perfluorocarboxylic acids and fluorooctane sulfonamide in human serum was developed. Importance was attached to the application of small ...

A critical review on occurrence, speciation, mobilization, and toxicity of per- and polyfluoroalkyl substances in the soil-microbe-plant system and bioremediation strategies.

Journal of hazardous materials
Per- and polyfluoroalkyl substances (PFAS) are a group of recalcitrant anthropogenic compounds that are extensively utilized for numerous industrial applications globally. Despite such vast utilization, PFAS accumulation in the soils and sediments wi...

Elucidating environmental fate and toxicological mechanisms of ultrashort- and short-chain PFAS: Integrating machine learning, molecular modeling, and experimental validation.

Journal of environmental management
Per- and polyfluoroalkyl substances (PFAS), due to their recalcitrance, toxicity, and widespread environmental distribution, have emerged as a critical public health concern. The fate of ultrashort- and short-chain PFAS in the heterogeneous environme...

Letter to the Editor regarding "Prediction of PFAS bioaccumulation in different plant tissues with machine learning models based on molecular fingerprints" by Song et al. (2024), Sci. Total Environ. 950 175091.

The Science of the total environment
Song et al. (2024), "Prediction of PFAS bioaccumulation in different plant tissues with machine learning models based on molecular fingerprints," employed machine learning methods, such as XGBoost and SHapley Additive exPlanations (SHAP), to predict ...

Advancements in artificial intelligence-based technologies for PFAS detection, monitoring, and management.

The Science of the total environment
Per- and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants with strong carbon‑fluorine (CF) bonds that contribute to bioaccumulation and long-term environmental and health risks. Traditional PFAS detection and treatment meth...

Predicting Bioconcentration Factors of Per- and Polyfluoroalkyl Substances Using a Directed Message Passing Neural Network with Multimodal Feature Fusion.

Environmental science & technology
Amid growing concerns regarding the ecological risks posed by emerging contaminants, per- and polyfluoroalkyl substances (PFASs) present significant challenges for risk assessment due to their structural diversity and the paucity of experimental data...

Integrative network and computational toxicology reveal the molecular mechanisms in PFOA-induced spermatogenic disorder.

Journal of environmental management
Perfluorooctanoic acid (PFOA), a widely used industrial chemical, poses significant environmental and biological toxicity, particularly affecting reproductive health. This study aimed to integrate network toxicology, machine learning, and molecular d...