AI Medical Compendium Topic:
Genomics

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Large-scale genomic survey with deep learning-based method reveals strain-level phage specificity determinants.

GigaScience
BACKGROUND: Phage therapy, reemerging as a promising approach to counter antimicrobial-resistant infections, relies on a comprehensive understanding of the specificity of individual phages. Yet the significant diversity within phage populations prese...

A Comprehensive System for Searching and Evaluating Genomic Variant Evidence Using AI and Knowledge Bases to Support Personalized Medicine.

AMIA ... Annual Symposium proceedings. AMIA Symposium
We introduce an innovative automated system for the search and assessment of genetic variant evidence, meticulously aligned with ACMG guidelines. Leveraging the synergistic power of artificial intelligence (AI), elastic search, and an extensive knowl...

Artificial Intelligence in Bone Metastasis Imaging: Recent Progresses from Diagnosis to Treatment - A Narrative Review.

Critical reviews in oncogenesis
The introduction of artificial intelligence (AI) represents an actual revolution in the radiological field, including bone lesion imaging. Bone lesions are often detected both in healthy and oncological patients and the differential diagnosis can be ...

The Role of Artificial Intelligence and Texture Analysis in Interventional Radiological Treatments of Liver Masses: A Narrative Review.

Critical reviews in oncogenesis
Liver lesions, including both benign and malignant tumors, pose significant challenges in interventional radiological treatment planning and prognostication. The emerging field of artificial intelligence (AI) and its integration with texture analysis...

Multi-omics Combined with Machine Learning Facilitating the Diagnosis of Gastric Cancer.

Current medicinal chemistry
Gastric cancer (GC) is a highly intricate gastrointestinal malignancy. Early detection of gastric cancer forms the cornerstone of precision medicine. Several studies have been conducted to investigate early biomarkers of gastric cancer using genomics...

Revolutionizing Biological Science: The Synergy of Genomics in Health, Bioinformatics, Agriculture, and Artificial Intelligence.

Omics : a journal of integrative biology
With climate emergency, COVID-19, and the rise of planetary health scholarship, the binary of human and ecosystem health has been deeply challenged. The interdependence of human and nonhuman animal health is increasingly acknowledged and paving the w...

Explainable artificial intelligence for omics data: a systematic mapping study.

Briefings in bioinformatics
Researchers increasingly turn to explainable artificial intelligence (XAI) to analyze omics data and gain insights into the underlying biological processes. Yet, given the interdisciplinary nature of the field, many findings have only been shared in ...

SSLpheno: a self-supervised learning approach for gene-phenotype association prediction using protein-protein interactions and gene ontology data.

Bioinformatics (Oxford, England)
MOTIVATION: Medical genomics faces significant challenges in interpreting disease phenotype and genetic heterogeneity. Despite the establishment of standardized disease phenotype databases, computational methods for predicting gene-phenotype associat...

Tensor Decomposition-based Feature Extraction and Classification to Detect Natural Selection from Genomic Data.

Molecular biology and evolution
Inferences of adaptive events are important for learning about traits, such as human digestion of lactose after infancy and the rapid spread of viral variants. Early efforts toward identifying footprints of natural selection from genomic data involve...