AI Medical Compendium Topic

Explore the latest research on artificial intelligence and machine learning in medicine.

Graph Neural Networks

Showing 21 to 30 of 99 articles

Clear Filters

SympGNNs: Symplectic Graph Neural Networks for identifying high-dimensional Hamiltonian systems and node classification.

Neural networks : the official journal of the International Neural Network Society
Existing neural network models to learn Hamiltonian systems, such as SympNets, although accurate in low-dimensions, struggle to learn the correct dynamics for high-dimensional many-body systems. Herein, we introduce Symplectic Graph Neural Networks (...

Adaptive node-level weighted learning for directed graph neural network.

Neural networks : the official journal of the International Neural Network Society
Directed graph neural networks (DGNNs) have garnered increasing interest, yet few studies have focused on node-level representation in directed graphs. In this paper, we argue that different nodes rely on neighbor information from different direction...

A graph neural network explainability strategy driven by key subgraph connectivity.

Journal of biomedical informatics
Current explainability strategies for Graph Neural Networks (GNNs) often focus on individual nodes or edges, neglecting the significance of key subgraphs in decision-making processes. This limitation can result in dispersed and less reliable explanat...

TopEC: prediction of Enzyme Commission classes by 3D graph neural networks and localized 3D protein descriptor.

Nature communications
Tools available for inferring enzyme function from general sequence, fold, or evolutionary information are generally successful. However, they can lead to misclassification if a deviation in local structural features influences the function. Here, we...

H2GnnDTI: hierarchical heterogeneous graph neural networks for drug-target interaction prediction.

Bioinformatics (Oxford, England)
MOTIVATION: Identifying drug-target interactions (DTIs) is a crucial step in drug repurposing and drug discovery. The significant increase in demand and the expensive nature for experimentally identifying DTIs necessitate computational tools for auto...

Graph neural networks for single-cell omics data: a review of approaches and applications.

Briefings in bioinformatics
Rapid advancement of sequencing technologies now allows for the utilization of precise signals at single-cell resolution in various omics studies. However, the massive volume, ultra-high dimensionality, and high sparsity nature of single-cell data ha...

Predicting orthognathic surgery results as postoperative lateral cephalograms using graph neural networks and diffusion models.

Nature communications
Orthognathic surgery, or corrective jaw surgery, is performed to correct severe dentofacial deformities and is increasingly sought for cosmetic purposes. Accurate prediction of surgical outcomes is essential for selecting the optimal treatment plan a...

Graph Neural Networks with Coarse- and Fine-Grained Division for mitigating label noise and sparsity.

Neural networks : the official journal of the International Neural Network Society
Graph Neural Networks (GNNs) have gained considerable prominence in semi-supervised learning tasks in processing graph-structured data, primarily owing to their message-passing mechanism, which largely relies on the availability of clean labels. Howe...

Heterogeneous Graph Neural Network with Adaptive Relation Reconstruction.

Neural networks : the official journal of the International Neural Network Society
Topological structures of real-world graphs often exhibit heterogeneity involving diverse nodes and relation types. In recent years, heterogeneous graph learning methods utilizing meta-paths to capture composite relations and guide neighbor selection...

Cox-Sage: enhancing Cox proportional hazards model with interpretable graph neural networks for cancer prognosis.

Briefings in bioinformatics
High-throughput sequencing technologies have facilitated a deeper exploration of prognostic biomarkers. While many deep learning (DL) methods primarily focus on feature extraction or employ simplistic fully connected layers within prognostic modules,...