AIMC Topic: HIV Infections
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The Intersections of COVID-19, HIV, and Race/Ethnicity: Machine Learning Methods to Identify and Model Risk Factors for Severe COVID-19 in a Large U.S. National Dataset.
AIDS and behavior
Feb 7, 2024
We investigate risk factors for severe COVID-19 in persons living with HIV (PWH), including among racialized PWH, using the U.S. population-sampled National COVID Cohort Collaborative (N3C) data released from January 1, 2020 to October 10, 2022. We d...
Comparison between a deep-learning and a pixel-based approach for the automated quantification of HIV target cells in foreskin tissue.
Scientific reports
Jan 23, 2024
The availability of target cells expressing the HIV receptors CD4 and CCR5 in genital tissue is a critical determinant of HIV susceptibility during sexual transmission. Quantification of immune cells in genital tissue is therefore an important outcom...
Enriching Data Science and Health Care Education: Application and Impact of Synthetic Data Sets Through the Health Gym Project.
JMIR medical education
Jan 16, 2024
Large-scale medical data sets are vital for hands-on education in health data science but are often inaccessible due to privacy concerns. Addressing this gap, we developed the Health Gym project, a free and open-source platform designed to generate s...
antibacterial activity of antiretroviral drugs on key commensal bacteria from the human microbiota.
Frontiers in cellular and infection microbiology
Jan 8, 2024
INTRODUCTION: Antiretroviral therapy has improved life expectancy in HIV-infected patients. However, people living with HIV under antiretroviral therapy are at higher risks of developing chronic complications and acquiring multidrug resistant bacteri...
Supervised machine learning algorithms to predict the duration and risk of long-term hospitalization in HIV-infected individuals: a retrospective study.
Frontiers in public health
Jan 5, 2024
OBJECTIVE: The study aimed to use supervised machine learning models to predict the length and risk of prolonged hospitalization in PLWHs to help physicians timely clinical intervention and avoid waste of health resources.
Cases of Monkeypox show highly-overlapping co-infection with HIV and syphilis.
Frontiers in public health
Jan 5, 2024
PURPOSE: Ongoing Monkeypox (MPX) outbreaks in countries outside Africa have unique characteristics. However, data on cohorts of confirmed cases in China is limited. The study provides important epidemiological, diagnostic, and clinical information ab...
Virological Findings and Treatment Outcomes of Cases That Developed Dolutegravir Resistance in Malawi's National HIV Treatment Program.
Viruses
Dec 23, 2023
Millions of Africans are on dolutegravir-based antiretroviral therapy (ART), but few detailed descriptions of dolutegravir resistance and its clinical management exist. We reviewed HIV drug resistance (HIVDR) testing application forms submitted betwe...
Deployment and assessment of a deep learning model for real-time detection of anal precancer with high frame rate high-resolution microendoscopy.
Scientific reports
Dec 14, 2023
Anal cancer incidence is significantly higher in people living with HIV as HIV increases the oncogenic potential of human papillomavirus. The incidence of anal cancer in the United States has recently increased, with diagnosis and treatment hampered ...
Computational drug discovery on human immunodeficiency virus with a customized long short-term memory variational autoencoder deep-learning architecture.
CPT: pharmacometrics & systems pharmacology
Dec 5, 2023
Despite attempts to control the spread of human immunodeficiency virus (HIV) through the use of anti-HIV medications, the absence of an effective vaccine continues to present a significant obstacle. In addition, the development of drug resistance by ...
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