IEEE/ACM transactions on computational biology and bioinformatics
Apr 6, 2021
Drug repurposing is a vital function in pharmaceutical fields and has gained popularity in recent years in both the pharmaceutical industry and research community. It refers to the process of discovering new uses and indications for existing or faile...
IEEE/ACM transactions on computational biology and bioinformatics
Apr 6, 2021
Increasing evidences revealed that microRNAs (miRNAs) play critical roles in important biological processes. The identification of disease-related miRNAs is critical to understand the molecular mechanisms of human diseases. Most existing computationa...
IEEE/ACM transactions on computational biology and bioinformatics
Apr 6, 2021
Computational drug repositioning, which is an efficient approach to find potential indications for drugs, has been used to increase the efficiency of drug development. The drug repositioning problem essentially is a top-K recommendation task that rec...
IEEE/ACM transactions on computational biology and bioinformatics
Apr 6, 2021
Survival analysis is a popular branch of statistics. At present, many algorithms (like traditional multi-tasking learning model) cannot be applied well in practice because of censored data. Although using some model (like parametric regression model)...
IEEE/ACM transactions on computational biology and bioinformatics
Apr 6, 2021
High-throughput screening technologies have provided a large amount of drug sensitivity data for a panel of cancer cell lines and hundreds of compounds. Computational approaches to analyzing these data can benefit anticancer therapeutics by identifyi...
IEEE/ACM transactions on computational biology and bioinformatics
Apr 6, 2021
Single nucleotide polymorphisms (SNPs) are one type of genetic variations and each SNP represents a difference in a single DNA building block, namely a nucleotide. Previous research demonstrated that SNPs can be used to identify the correct source po...
IEEE/ACM transactions on computational biology and bioinformatics
Apr 6, 2021
Mitosis detection is one of the challenging steps in biomedical imaging research, which can be used to observe the cell behavior. Most of the already existing methods that are applied in detecting mitosis usually contain many nonmitotic events (norma...
PURPOSE: We aimed to introduce an explainable machine learning technology to help clinicians understand the risk factors for neonatal postoperative mortality at different levels.
Computer mouse tracking offers a simple and cost-efficient way to gather continuous behavioral data and has mostly been utilized in psychological science to study cognitive processes. The present study extends the potential applicability of computer ...
Neural networks : the official journal of the International Neural Network Society
Apr 5, 2021
Respiration is an essential and primary mechanism for speech production. We first inhale and then produce speech while exhaling. When we run out of breath, we stop speaking and inhale. Though this process is involuntary, speech production involves a ...
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