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Design and Development of a Topology-Optimized Three-Dimensional Printed Soft Gripper.

Soft robotics
In the past decade, a rich repertoire of soft robots, designed from biomimetic and intuitive approaches, has been developed to overcome challenges faced by their rigid-bodied counterparts. However, these design approaches are greatly limited by the d...

Enabling Precision Medicine through Integrative Network Models.

Journal of molecular biology
A key challenge in precision medicine lies in understanding molecular-level underpinnings of complex human disease. Biological networks in multicellular organisms can generate hypotheses about disease genes, pathways, and their behavior in disease-re...

Modeling the covariates effects on the hazard function by piecewise exponential artificial neural networks: an application to a controlled clinical trial on renal carcinoma.

BMC bioinformatics
BACKGROUND: In exploring the time course of a disease to support or generate biological hypotheses, the shape of the hazard function provides relevant information. For long follow-ups the shape of hazard function may be complex, with the presence of ...

Convolutional Neural Network for Segmentation and Measurement of Intima Media Thickness.

Journal of medical systems
The measurement of Carotid Intima Media Thickness (IMT) on Common Carotid Artery (CCA) is a principle marker of risk of cardiovascular disease. This paper presents a novel method of using deep Convolutional Neural Network (CNN) for identification and...

Automatic Annotation for Human Activity Recognition in Free Living Using a Smartphone.

Sensors (Basel, Switzerland)
Data annotation is a time-consuming process posing major limitations to the development of Human Activity Recognition (HAR) systems. The availability of a large amount of labeled data is required for supervised Machine Learning (ML) approaches, espec...

Unsupervised Machine Learning to Identify High Likelihood of Dementia in Population-Based Surveys: Development and Validation Study.

Journal of medical Internet research
BACKGROUND: Dementia is increasing in prevalence worldwide, yet frequently remains undiagnosed, especially in low- and middle-income countries. Population-based surveys represent an underinvestigated source to identify individuals at risk of dementia...

Public Perception Analysis of Tweets During the 2015 Measles Outbreak: Comparative Study Using Convolutional Neural Network Models.

Journal of medical Internet research
BACKGROUND: Timely understanding of public perceptions allows public health agencies to provide up-to-date responses to health crises such as infectious diseases outbreaks. Social media such as Twitter provide an unprecedented way for the prompt asse...
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Proactive expert system intervention to prevent or quit at-risk alcohol use (PRINT): study protocol of a randomized controlled trial.

BMC public health
BACKGROUND: The population impact of alcohol screening and brief intervention might be increased by approaching an entire population rather than individuals at high risk only. The aim is to present the protocol of the study "Testing a proactive exper...