The United States is in the midst of a prescription opioid epidemic, with the number of yearly opioid-related overdose deaths increasing almost fourfold since 2000. To more effectively prevent unintentional opioid overdoses, the medical profession re...
As individuals age, there is potential for dramatic changes in the social and behavioral determinants that affect health status and outcomes. The importance of these determinants has been increasingly recognized in clinical decision-making. We sought...
In this paper, we propose a novel neural network architecture for clinical text mining. We formulate this hybrid neural network model (HNN), composed of recurrent neural network and deep residual network, to jointly predict the presence and period as...
Gleason grading of histological images is important in risk assessment and treatment planning for prostate cancer patients. Much research has been done in classifying small homogeneous cancer regions within histological images. However, semi-supervis...
De-identification of clinical notes is a special case of named entity recognition. Supervised machine-learning (ML) algorithms have achieved promising results for this task. However, ML-based de-identification systems often require annotating a large...
Classifying relations between pairs of medical concepts in clinical texts is a crucial task to acquire empirical evidence relevant to patient care. Due to limited labeled data and extremely unbalanced class distributions, medical relation classificat...
Data augmentation is an essential part of training discriminative Convolutional Neural Networks (CNNs). A variety of augmentation strategies, including horizontal flips, random crops, and principal component analysis (PCA), have been proposed and sho...
Models have been developed to predict stroke outcomes (e.g., mortality) in attempt to provide better guidance for stroke treatment. However, there is little work in developing classification models for the problem of unknown time-since-stroke (TSS), ...
There is growing interest in applying machine learning methods to Electronic Medical Records (EMR). Across different institutions, however, EMR quality can vary widely. This work investigated the impact of this disparity on the performance of three a...
The clinical, granular data in electronic health record (EHR) systems provide opportunities to improve patient care using informatics retrieval methods. However, it is well known that many methodological obstacles exist in accessing data within EHRs....
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