BACKGROUND: 16S rRNA amplicon sequencing is a widely used method for microbiome composition analysis due to its cost-effectiveness and lower data requirements compared to metagenomic whole-genome sequencing (WGS). However, inherent limitations in 16S...
Engineered T-cell receptor (eTCR) systems rely on accurately generated T-cell receptor (TCR) sequences to enhance immunotherapy predictability and efficacy. The most variable and crucial part of the TCR receptor is the CDR3 sequence region. Current m...
Developmental Dysplasia of the Hip (DDH) stands as one of the preeminent hip disorders prevalent in pediatric orthopedics. Automated diagnostic instruments, driven by artificial intelligence methodologies, are capable of providing substantial assista...
Electrocardiogram (ECG) is a common non-invasive diagnostic tool for cardiovascular diseases. Adequate data is crucial in utilizing deep learning to achieve intelligent diagnosis of ECG. The existing ECG datasets almost only focus on adults and most ...
BACKGROUND: In Germany, there are still many young people with gaming disorder (GD) who do not use or cannot access existing treatment services. Given the increasing prevalence of internet use disorders and GD, especially among young people in German...
BACKGROUND: Electronic health records (EHRs) are widely used in health care systems across the United States to help clinicians access patient medical histories in one central location. As medical knowledge expands, clinicians are increasingly using ...
BACKGROUND: Chronic obstructive pulmonary disease (COPD), marked by dyspnea, cough, and sputum production, significantly impairs patients' quality of life and functionality. Effective management strategies, particularly those empowering patients to m...
Journal of computer-aided molecular design
May 26, 2025
Rickettsia is a genus of bacteria that are obligate intracellular parasites and are responsible for the febrile diseases known collectively as Rickettsioses. The emergence of antibiotic resistance is an escalating concern and thus developing a vaccin...
PURPOSE OF REVIEW: Renal cell carcinoma (RCC) is a prevalent and increasingly diagnosed malignancy associated with high mortality and recurrence rates. Traditional diagnostic and therapeutic approaches have limitations due to the disease's molecular ...
OBJECTIVE: The determination of the mid-sagittal plane (MSP) on three-dimensional (3D) head imaging is key to the assessment of facial asymmetry. The aim of this study was to evaluate the reliability of an automated landmark-based MSP to quantify man...
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