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Inflammatory Bowel Diseases

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Plasma Epstein-Barr Virus DNA load for diagnostic and prognostic assessment in intestinal Epstein-Barr Virus infection.

Frontiers in cellular and infection microbiology
BACKGROUND: The prospective application of plasma Epstein-Barr virus (EBV) DNA load as a noninvasive measure of intestinal EBV infection remains unexplored. This study aims to identify ideal threshold levels for plasma EBV DNA loads in the diagnosis ...

Automated Endoscopic Diagnosis in IBD: The Emerging Role of Artificial Intelligence.

Gastrointestinal endoscopy clinics of North America
The emerging role of artificial intelligence (AI) in automated endoscopic diagnosis represents a significant advancement in managing inflammatory bowel disease (IBD). AI technologies are increasingly being applied to endoscopic imaging to enhance the...

Artificial Intelligence in Inflammatory Bowel Disease.

Gastrointestinal endoscopy clinics of North America
Artificial intelligence (AI) is being increasingly studied and implemented in gastroenterology. In inflammatory bowel disease (IBD), numerous AI models are being developed to assist with IBD diagnosis, standardization of endoscopic and radiologic dis...

Development of a deep learning algorithm for Paneth cell density quantification for inflammatory bowel disease.

EBioMedicine
BACKGROUND: Alterations in ileal Paneth cell (PC) density have been described in gut inflammatory diseases such as Crohn's disease (CD) and could be used as a biomarker for disease prognosis. However, quantifying PCs is time-intensive, a barrier for ...

Unravelling metabolite-microbiome interactions in inflammatory bowel disease through AI and interaction-based modelling.

Biochimica et biophysica acta. Molecular basis of disease
Inflammatory Bowel Diseases (IBDs) are chronic inflammatory disorders of the gastrointestinal tract and colon affecting approximately 7 million individuals worldwide. The knowledge of specific pathology and aetiological mechanisms leading to IBD is l...

Deep Learning for Classification of Inflammatory Bowel Disease Activity in Whole Slide Images of Colonic Histopathology.

The American journal of pathology
Grading activity of inflammatory bowel disease (IBD) using standardized histopathological scoring systems remains challenging due to limited availability of pathologists with IBD expertise and interobserver variability. In this study, a deep learning...

Prevalence, incidence, and mortality of inflammatory bowel disease in the Netherlands: development and external validation of machine learning models.

Journal of Crohn's & colitis
BACKGROUND AND AIMS: Large registries are promising tools to study the epidemiology of inflammatory bowel disease (IBD). We aimed to develop and validate machine learning models to identify IBD cases in administrative data, aiming to determine the pr...

Machine learning prediction of premature death from multimorbidity among people with inflammatory bowel disease: a population-based retrospective cohort study.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
BACKGROUND: Multimorbidity, the co-occurrence of 2 or more chronic conditions, is important in patients with inflammatory bowel disease (IBD) given its association with complex care plans, poor health outcomes, and excess mortality. Our objectives we...

Enhancing patient representation learning with inferred family pedigrees improves disease risk prediction.

Journal of the American Medical Informatics Association : JAMIA
BACKGROUND: Machine learning and deep learning are powerful tools for analyzing electronic health records (EHRs) in healthcare research. Although family health history has been recognized as a major predictor for a wide spectrum of diseases, research...

Artificial intelligence-assisted approach to assessing bowel wall thickness in pediatric inflammatory bowel disease using intestinal ultrasound images.

Journal of Crohn's & colitis
BACKGROUND AND AIM: Intestinal ultrasound (IUS) potentially spares patients from repeated endoscopies under sedation and eliminates the need for alternative imaging modalities like magnetic resonance enterography and computed tomography enterography ...