BACKGROUND: Drug-drug interactions (DDIs) are a major concern, especially for older adults taking multiple medications. Although Health Canada and the US Food and Drug Administration (FDA) use population-based studies to identify adverse drug events,...
BACKGROUND: Housing and income are important social determinants of health (SDoH). Primary care providers often do not have information about these determinants, which could be used to support equitable health system planning and care delivery. The a...
BACKGROUND: Cigarette smoking is a leading cause of preventable morbidity and mortality worldwide. Women who smoke face greater health risks than men, including higher rates of cardiovascular disease and more pronounced declines in lung function. Des...
Land use regression (LUR) models assess air pollution exposure but often struggle with transferability (predicting concentrations in areas without measurements) and generalizability (capturing spatial patterns across neighborhoods). This study evalua...
IMPORTANCE: Clinical artificial intelligence (AI) systems are susceptible to performance degradation due to data shifts, which can lead to erroneous predictions and potential patient harm. Proactively detecting and mitigating these shifts is crucial ...
Early diagnosis and access to resources, support and therapy are critical for improving long-term outcomes for children with autism spectrum disorder (ASD). ASD is typically detected using a case-finding approach based on symptoms and family history,...
BACKGROUND: Chronic pain is a complex condition that affects more than a quarter of people worldwide. The development and progression of chronic pain are unique to each individual due to the contribution of interacting biological, psychological, and ...
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
Mar 24, 2025
BACKGROUND: Multimorbidity, the co-occurrence of 2 or more chronic conditions, is important in patients with inflammatory bowel disease (IBD) given its association with complex care plans, poor health outcomes, and excess mortality. Our objectives we...
American journal of veterinary research
Feb 11, 2025
OBJECTIVE: Lyme disease is a vector-borne emerging zoonosis in Ontario driven by human population growth and climate change. Lyme disease is also a prime example of the One Health concept. While little can be done to immediately reverse climate chang...
Ophthalmic surgery, lasers & imaging retina
Feb 1, 2025
BACKGROUND AND OBJECTIVE: This study evaluated optometrists' referral patterns for epiretinal membrane (ERM) patients in Ontario, Canada, and their attitudes towards an artificial intelligence (AI) tool for improving referral accuracy. An anonymous o...
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