AIMC Topic: Insulin Resistance

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The Use of Machine Learning Techniques to Determine the Predictive Value of Inflammatory Biomarkers in the Development of Type 2 Diabetes Mellitus.

Metabolic syndrome and related disorders
Certain inflammatory biomarkers, such as interleukin-6, interleukin-1, C-reactive protein (CRP), and fibrinogen, are prototypical acute-phase parameters that can also be predictors of cardiovascular disease. However, this inflammatory response can a...

Trace element, immune and opioid biomarkers of unstable angina, increased atherogenicity and insulin resistance: Results of machine learning.

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
BACKGROUND: Aberrations in endothelial cells, immune and oxidative pathways are associated with atherosclerosis (ATS) and unstable angina (UA). The role of trace elements, minerals, and the endogenous opioid system (EOS) in UA are less well establish...

[Leptin sexual dimorphism, insulin resistance, and body composition in normal weight prepubescent].

Revista chilena de pediatria
INTRODUCTION: The prepubertal stage is a critical period of body fat development, in which leptin and insulin re sistance has been associated, however, there are few studies in normal-weight prepubescents. Ob jective: To assess the relationship betwe...

Predicting long-term type 2 diabetes with support vector machine using oral glucose tolerance test.

PloS one
Diabetes is a large healthcare burden worldwide. There is substantial evidence that lifestyle modifications and drug intervention can prevent diabetes, therefore, an early identification of high risk individuals is important to design targeted preven...

Different spexin level in obese vs normal weight children and its relationship with obesity related risk factors.

Nutrition, metabolism, and cardiovascular diseases : NMCD
BACKGROUND AND AIMS: Spexin (SPX) is a novel peptide recently discovered as an important regulatory adipokine in obesity and related metabolic diseases. The aim of the current study was to determine the potential role of Circulating levels of SPX in ...

TyG-er: An ensemble Regression Forest approach for identification of clinical factors related to insulin resistance condition using Electronic Health Records.

Computers in biology and medicine
BACKGROUND: Insulin resistance is an early-stage deterioration of Type 2 diabetes. Identification and quantification of insulin resistance requires specific blood tests; however, the triglyceride-glucose (TyG) index can provide a surrogate assessment...

Picomolar detection of retinol binding protein 4 for early management of type II diabetes.

Biosensors & bioelectronics
Type (II) diabetes is one of the major threats to mankind as it causes insulin resistance in human body and Retinol Binding Protein 4 (RBP4) is currently considered as a potential biomarker for early management of this disease. Hence a low-level dete...

Insulin resistance and adrenal incidentalomas: A bidirectional relationship.

Maturitas
An adrenal incidentaloma (AI) is an adrenal mass incidentally found via a radiological modality, independent of an endocrinological investigation. In this review, we aimed to investigate the possible reasons behind the increased frequency in AI detec...

High waist-to-hip ratio levels are associated with insulin resistance markers in normal-weight women.

Diabetes & metabolic syndrome
AIM: To assess the association between high waist-to-hip ratio (WHR) levels and insulin resistance (IR) or hyperinsulinemia after oral glucose tolerance test (OGTT) in a sample of normal-weight women.

Circulating betatrophin in relation to metabolic, inflammatory parameters, and oxidative stress in patients with type 2 diabetes mellitus.

Diabetes & metabolic syndrome
AIMS: Recently, it was suggested that betatrophin has a role in controlling pancreatic β cell proliferation and lipid metabolism, however, its role in human subjects has not been established yet. The predicting role of betatrophin and MDA along with ...