AIMC Topic: Insulin Resistance

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Picomolar detection of retinol binding protein 4 for early management of type II diabetes.

Biosensors & bioelectronics
Type (II) diabetes is one of the major threats to mankind as it causes insulin resistance in human body and Retinol Binding Protein 4 (RBP4) is currently considered as a potential biomarker for early management of this disease. Hence a low-level dete...

Insulin resistance and adrenal incidentalomas: A bidirectional relationship.

Maturitas
An adrenal incidentaloma (AI) is an adrenal mass incidentally found via a radiological modality, independent of an endocrinological investigation. In this review, we aimed to investigate the possible reasons behind the increased frequency in AI detec...

High waist-to-hip ratio levels are associated with insulin resistance markers in normal-weight women.

Diabetes & metabolic syndrome
AIM: To assess the association between high waist-to-hip ratio (WHR) levels and insulin resistance (IR) or hyperinsulinemia after oral glucose tolerance test (OGTT) in a sample of normal-weight women.

Circulating betatrophin in relation to metabolic, inflammatory parameters, and oxidative stress in patients with type 2 diabetes mellitus.

Diabetes & metabolic syndrome
AIMS: Recently, it was suggested that betatrophin has a role in controlling pancreatic β cell proliferation and lipid metabolism, however, its role in human subjects has not been established yet. The predicting role of betatrophin and MDA along with ...

High triglycerides to HDL-cholesterol ratio is associated with insulin resistance in normal-weight healthy adults.

Diabetes & metabolic syndrome
AIM: To evaluate the association between high triglyceride/HDL-cholesterol (TG/HDL-C) ratio and insulin resistance (IR) or hyperinsulinemia after oral glucose tolerance test (OGTT) in normal-weight healthy adults.

Triglycerides and glucose index as an insulin resistance marker in a sample of healthy adults.

Diabetes & metabolic syndrome
AIM: To assess the association between elevated triglycerides/glucose index (TGI) and insulin resistance (IR) or hyperinsulinemia after oral glucose tolerance test (OGTT) in a sample of healthy adults.

Association between vitamin D deficiency and insulin resistance markers in euthyroid non-diabetic individuals.

Diabetes & metabolic syndrome
AIM: To evaluate the association between vitamin D deficiency and insulin resistance (IR) or hyperinsulinemia after oral glucose tolerance test (OGTT) in euthyroid non-diabetic individuals.

Improved perfusion pattern score association with type 2 diabetes severity using machine learning pipeline: Pilot study.

Journal of magnetic resonance imaging : JMRI
BACKGROUND: Type 2 diabetes mellitus (T2DM) is associated with alterations in the blood-brain barrier, neuronal damage, and arterial stiffness, thus affecting cerebral metabolism and perfusion. There is a need to implement machine-learning methodolog...

Plasminogen activator inhibitor-1 is associated with the metabolism and development of advanced colonic polyps.

Translational research : the journal of laboratory and clinical medicine
Implications of plasminogen activator inhibitor-1 (PAI-1) in colonic polyps remain elusive. A prospective study was conducted with 188 consecutive subjects who underwent colonoscopy at a tertiary referral center. Biochemical parameters, serum PAI-1 l...

Fuzzy set-based generalized multifactor dimensionality reduction analysis of gene-gene interactions.

BMC medical genomics
BACKGROUND: Gene-gene interactions (GGIs) are a known cause of missing heritability. Multifactor dimensionality reduction (MDR) is one of most commonly used methods for GGI detection. The generalized multifactor dimensionality reduction (GMDR) method...