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Ischemic Stroke

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Development and validation of an interpretable machine learning model for predicting post-stroke epilepsy.

Epilepsy research
BACKGROUND: Epilepsy is a serious complication after an ischemic stroke. Although two studies have developed prediction model for post-stroke epilepsy (PSE), their accuracy remains insufficient, and their applicability to different populations is unc...

Identification of endoplasmic reticulum stress genes in human stroke based on bioinformatics and machine learning.

Neurobiology of disease
After ischemic stroke (IS), secondary injury is intimately linked to endoplasmic reticulum (ER) stress and body-brain crosstalk. Nonetheless, the underlying mechanism systemic immune disorder mediated ER stress in human IS remains unknown. In this st...

Multi-grained contrastive representation learning for label-efficient lesion segmentation and onset time classification of acute ischemic stroke.

Medical image analysis
Ischemic lesion segmentation and the time since stroke (TSS) onset classification from paired multi-modal MRI imaging of unwitnessed acute ischemic stroke (AIS) patients is crucial, which supports tissue plasminogen activator (tPA) thrombolysis decis...

Assessment of Deep Learning-Based Triage Application for Acute Ischemic Stroke on Brain MRI in the ER.

Academic radiology
RATIONALE AND OBJECTIVES: To assess a deep learning application (DLA) for acute ischemic stroke (AIS) detection on brain magnetic resonance imaging (MRI) in the emergency room (ER) and the effect of T2-weighted imaging (T2WI) on its performance.

Machine Learning-Based Etiologic Subtyping of Ischemic Stroke Using Circulating Exosomal microRNAs.

International journal of molecular sciences
Ischemic stroke is a major cause of mortality worldwide. Proper etiological subtyping of ischemic stroke is crucial for tailoring treatment strategies. This study explored the utility of circulating microRNAs encapsulated in extracellular vesicles (E...

Personalized prediction of mortality in patients with acute ischemic stroke using explainable artificial intelligence.

European journal of medical research
BACKGROUND: Research into the acute kidney disease (AKD) after acute ischemic stroke (AIS) is rare, and how clinical features influence its prognosis remain unknown. We aim to employ interpretable machine learning (ML) models to study AIS and clarify...

Systematic Review and Meta-Analysis of Prehospital Machine Learning Scores as Screening Tools for Early Detection of Large Vessel Occlusion in Patients With Suspected Stroke.

Journal of the American Heart Association
BACKGROUND: Enhanced detection of large vessel occlusion (LVO) through machine learning (ML) for acute ischemic stroke appears promising. This systematic review explored the capabilities of ML models compared with prehospital stroke scales for LVO pr...

Prediagnosis recognition of acute ischemic stroke by artificial intelligence from facial images.

Aging cell
Stroke is a major threat to life and health in modern society, especially in the aging population. Stroke may cause sudden death or severe sequela-like hemiplegia. Although computed tomography (CT) and magnetic resonance imaging (MRI) are standard di...

Hybrid CNN-Transformer Network With Circular Feature Interaction for Acute Ischemic Stroke Lesion Segmentation on Non-Contrast CT Scans.

IEEE transactions on medical imaging
Lesion segmentation is a fundamental step for the diagnosis of acute ischemic stroke (AIS). Non-contrast CT (NCCT) is still a mainstream imaging modality for AIS lesion measurement. However, AIS lesion segmentation on NCCT is challenging due to low c...

Artificial intelligence to predict individualized outcome of acute ischemic stroke patients: The SIBILLA project.

European stroke journal
INTRODUCTION: Formulating reliable prognosis for ischemic stroke patients remains a challenging task. We aimed to develop an artificial intelligence model able to formulate in the first 24 h after stroke an individualized prognosis in terms of NIHSS.