AIMC Topic: Klebsiella Infections

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Discrimination of Klebsiella pneumoniae and Klebsiella quasipneumoniae by MALDI-TOF Mass Spectrometry Coupled With Machine Learning.

MicrobiologyOpen
Klebsiella species, including Klebsiella pneumoniae and Klebsiella quasipneumoniae, present significant challenges in clinical microbiology due to their genetic similarity, which complicates accurate species identification using established methods, ...

Decoding virulence and resistance in Klebsiella pneumoniae: Pharmacological insights, immunological dynamics, and in silico therapeutic strategies.

Microbial pathogenesis
Klebsiella pneumoniae (K. pneumoniae) has become a serious global health concern due to its rising virulence and antibiotic resistance. As one of the leading members of ESKAPE pathogens, it plays a major role in a wide range of infections that cause ...

Rapid Identification and Typing of Carbapenem-Resistant Klebsiella pneumoniae Using MALDI-TOF MS and Machine Learning.

Microbial biotechnology
Use matrix-assisted laser desorption ionisation time-of-flight mass spectrometry (MALDI-TOF MS) to screen the specific mass peaks of carbapenem-resistant Klebsiella pneumoniae (CRKP), compare the differences in spectrum peaks between intestinal and b...

Precise Detection of Carbapenem-Resistant and Hypervirulent Using MOF-Derived Bimetallic Nanocube Hybrid Nanosheet.

Analytical chemistry
Carbapenem resistance and hypervirulence represent two distinct evolutionary pathways in , posing significant challenges in clinical settings. Of particular concern are convergent strains that combine both traits, complicating timely diagnosis and tr...

Machine learning for identifying resistance features of using whole-genome sequence single nucleotide polymorphisms.

Journal of medical microbiology
, a gram-negative bacterium, is a common pathogen causing nosocomial infection. The drug-resistance rate of is increasing year by year, posing a severe threat to public health worldwide. has been listed as one of the pathogens causing the global c...