AIMC Topic: Immune Evasion
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Predicting viral proteins that evade the innate immune system: a machine learning-based immunoinformatics tool.
BMC bioinformatics
Nov 9, 2024
Viral proteins that evade the host's innate immune response play a crucial role in pathogenesis, significantly impacting viral infections and potential therapeutic strategies. Identifying these proteins through traditional methods is challenging and ...
Deep-Learning Resources for Studying Glycan-Mediated Host-Microbe Interactions.
Cell host & microbe
Oct 28, 2020
Glycans, the most diverse biopolymer, are shaped by evolutionary pressures stemming from host-microbe interactions. Here, we present machine learning and bioinformatics methods to leverage the evolutionary information present in glycans to gain insig...
Zwitterionic 3D-Printed Non-Immunogenic Stealth Microrobots.
Advanced materials (Deerfield Beach, Fla.)
Aug 30, 2020
Microrobots offer transformative solutions for non-invasive medical interventions due to their small size and untethered operation inside the human body. However, they must face the immune system as a natural protection mechanism against foreign thre...
Decoding virulence and resistance in Klebsiella pneumoniae: Pharmacological insights, immunological dynamics, and in silico therapeutic strategies.
Microbial pathogenesis
Aug 1, 2025
Klebsiella pneumoniae (K. pneumoniae) has become a serious global health concern due to its rising virulence and antibiotic resistance. As one of the leading members of ESKAPE pathogens, it plays a major role in a wide range of infections that cause ...
Computationally designed proteins mimic antibody immune evasion in viral evolution.
Immunity
Jun 10, 2025
Recurrent waves of viral infection necessitate vaccines and therapeutics that remain effective against emerging viruses. Our ability to evaluate interventions is currently limited to assessments against past or circulating variants, which likely diff...
Immune evasion by designer microrobots.
Science robotics
Jun 17, 2020
Recent work is unveiling the interactions between magnetic microswimmers and cells of the immune system.
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