AIMC Topic: Tetracyclines

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Ratiometric, 3D Fluorescence Spectrum with Abundant Information for Tetracyclines Discrimination via Dual Biomolecules Recognition and Deep Learning.

Analytical chemistry Mar 18, 2025
Tetracyclines are widely used in bacteria infection treatment, while the subtle chemical differences between tetracyclines make it a challenge to accurate discrimination via biosensors. A 3D fluorescence spectrum can provide fingerprint structure inf...
Deep Learning Aptamers, Nucleotide Neural Networks, Computer Tetracyclines Spectrometry, Fluorescence
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A MOF-on-MOF heterostructure ratiometric/colorimetric dual-mode fluorescence sensor based on support vector machine for detecting tetracyclines in animal-derived foods.

Food chemistry Jul 31, 2024
The misuse of tetracyclines in livestock production poses significant health risks. Thus, establishing convenient detection methods to replace complex laboratory tests for food safety is crucial. In this study, a heterostructure Zn-BTC/IRMOF-3 (denot...
Anti-Bacterial Agents Animals Support Vector Machine Food Contamination Limit of Detection Fluorescence Colorimetry Tetracyclines Spectrometry, Fluorescence Metal-Organic Frameworks
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Deep learning assisted logic gates for real-time identification of natural tetracycline antibiotics.

Food chemistry May 30, 2024
The overuse and misuse of tetracycline (TCs) antibiotics, including tetracycline (TTC), oxytetracycline (OTC), doxycycline (DC), and chlortetracycline (CTC), pose a serious threat to human health. However, current rapid sensing platforms for tetracyc...
Tetracyclines Tetracycline Deep Learning Colorimetry Food Contamination Logic Smartphone Anti-Bacterial Agents
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In vitro activity of eravacycline against 2213 Gram-negative and 2424 Gram-positive bacterial pathogens isolated in Canadian hospital laboratories: CANWARD surveillance study 2014-2015.

Diagnostic microbiology and infectious disease Dec 22, 2017
Gram-negative (n=2213) and Gram-positive (n=2424) pathogens isolated from patients in 13 Canadian hospitals in 2014 and 2015 were tested for in vitro susceptibility to eravacycline and comparators using the Clinical and Laboratory Standards Institute...
Laboratories, Hospital Tetracyclines Enterobacteriaceae Epidemiological Monitoring Gram-Positive Bacterial Infections Microbial Sensitivity Tests Gram-Positive Bacteria Gram-Negative Bacteria Gram-Negative Bacterial Infections Canada Enterobacteriaceae Infections Humans Anti-Bacterial Agents
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A Closed-Loop Environmental Health Management Platform: A Multifunctional MgFeO Nanoparticle Enabling AI-Enhanced Detection, Bioimaging, and Degradation of Tetracycline Antibiotics.

Analytical chemistry Jul 1, 2025
Emerging pollutants such as tetracycline antibiotics (TCs) have garnered attention due to their ecological impacts and the evolution of drug resistance. However, the comprehensive monitoring of TCs remains inadequate. This study presents a multifunct...
Nanoparticles Zebrafish Anti-Bacterial Agents Animals Tetracyclines Machine Learning Tetracycline Magnesium Compounds Ferric Compounds Optical Imaging
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Eravacycline, an antibacterial drug, repurposed for pancreatic cancer therapy: insights from a molecular-based deep learning model.

Briefings in bioinformatics Mar 27, 2024
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) remains a serious threat to health, with limited effective therapeutic options, especially due to advanced stage at diagnosis and its inherent resistance to chemotherapy, making it one of the leadin...
Tetracyclines Drug Repositioning Carcinoma, Pancreatic Ductal Cell Line, Tumor Cell Proliferation Apoptosis Pancreatic Neoplasms Antineoplastic Agents Cell Movement Deep Learning Humans Anti-Bacterial Agents
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Machine learning for identifying resistance features of using whole-genome sequence single nucleotide polymorphisms.

Journal of medical microbiology Nov 1, 2021
, a gram-negative bacterium, is a common pathogen causing nosocomial infection. The drug-resistance rate of is increasing year by year, posing a severe threat to public health worldwide. has been listed as one of the pathogens causing the global c...
Cross Infection Tetracyclines Amikacin Imipenem Genome, Bacterial Klebsiella Infections Gentamicins Polymorphism, Single Nucleotide Klebsiella pneumoniae Anti-Bacterial Agents Humans Microbial Sensitivity Tests Machine Learning Drug Resistance, Multiple, Bacterial
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