AI Medical Compendium Topic:
Knowledge Bases

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Testing the actual equivalence of automatically generated items.

Behavior research methods
If the automatic item generation is used for generating test items, the question of how the equivalence among different instances may be tested is fundamental to assure an accurate assessment. In the present research, the question was dealt by using ...

BioMuta and BioXpress: mutation and expression knowledgebases for cancer biomarker discovery.

Nucleic acids research
Single-nucleotide variation and gene expression of disease samples represent important resources for biomarker discovery. Many databases have been built to host and make available such data to the community, but these databases are frequently limited...

Gramene 2018: unifying comparative genomics and pathway resources for plant research.

Nucleic acids research
Gramene (http://www.gramene.org) is a knowledgebase for comparative functional analysis in major crops and model plant species. The current release, #54, includes over 1.7 million genes from 44 reference genomes, most of which were organized into 62,...

The Reactome Pathway Knowledgebase.

Nucleic acids research
The Reactome Knowledgebase (https://reactome.org) provides molecular details of signal transduction, transport, DNA replication, metabolism, and other cellular processes as an ordered network of molecular transformations-an extended version of a clas...

iPTMnet: an integrated resource for protein post-translational modification network discovery.

Nucleic acids research
Protein post-translational modifications (PTMs) play a pivotal role in numerous biological processes by modulating regulation of protein function. We have developed iPTMnet (http://proteininformationresource.org/iPTMnet) for PTM knowledge discovery, ...

SuperDRUG2: a one stop resource for approved/marketed drugs.

Nucleic acids research
Regular monitoring of drug regulatory agency web sites and similar resources for information on new drug approvals and changes to legal status of marketed drugs is impractical. It requires navigation through several resources to find complete informa...

ICG: a wiki-driven knowledgebase of internal control genes for RT-qPCR normalization.

Nucleic acids research
Real-time quantitative PCR (RT-qPCR) has become a widely used method for accurate expression profiling of targeted mRNA and ncRNA. Selection of appropriate internal control genes for RT-qPCR normalization is an elementary prerequisite for reliable ex...

miRandola 2017: a curated knowledge base of non-invasive biomarkers.

Nucleic acids research
miRandola (http://mirandola.iit.cnr.it/) is a database of extracellular non-coding RNAs (ncRNAs) that was initially published in 2012, foreseeing the relevance of ncRNAs as non-invasive biomarkers. An increasing amount of experimental evidence shows ...

Clinical Data Warehouse Query and Learning Tool Using a Human-Centered Participatory Design Process.

Studies in health technology and informatics
BMI Investigator (BMII) is an interactive web-based tool with a learning knowledge base, which provides a way for researchers to query structured, unstructured, genomic and image data contained in a data warehouse. We demonstrate how development of a...

Radiation Oncology Terminology Linker: A Step Towards a Linked Data Knowledge Base.

Studies in health technology and informatics
Performing image feature extraction in radiation oncology is often dependent on the organ and tumor delineations provided by clinical staff. These delineation names are free text DICOM metadata fields resulting in undefined information, which require...