AIMC Topic: Large Language Models

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Detecting Adverse Drug Events in Clinical Notes Using Large Language Models.

Studies in health technology and informatics
Monitoring adverse drug events (ADEs) is critical for pharmacovigilance and patient safety. However, identifying ADEs remains challenging, as suspected or confirmed side effects are often documented solely in the unstructured text of electronic healt...

Delirium Identification from Nursing Reports Using Large Language Models.

Studies in health technology and informatics
This study investigates large language models for delirium detection from nursing reports, comparing keyword matching, prompting, and finetuning. Using a manually labelled dataset from the University Hospital Freiburg, Germany, we tested Llama3 and P...

Exploring Zero-Shot Cross-Lingual Biomedical Concept Normalization via Large Language Models.

Studies in health technology and informatics
Over the past few years, discriminative and generative large language models (LLMs) have emerged as the predominant approaches in natural language processing. However, despite significant advancements, there remains a gap in comparing the performance...

Leveraging Large Language Models for Synthetic Data Generation to Enhance Adverse Drug Event Detection in Tweets.

Studies in health technology and informatics
Adverse drug event (ADE) detection in social media texts poses significant challenges due to the informal nature of the text and the limited availability of annotations. The scarcity of ADE named entity recognition (NER) datasets for social media hin...

Fine-Tuning an Existing Large Language Model with Knowledge from the Medical Expert System Hepaxpert.

Studies in health technology and informatics
The analysis and individual interpretation of hepatitis serology test results is a complex task in laboratory medicine, requiring either experienced physicians or specialized expert systems. This study explores fine-tuning a large language model (LLM...

Feasibility study of automatic radiotherapy treatment planning for cervical cancer using a large language model.

Radiation oncology (London, England)
BACKGROUND: Radiotherapy treatment planning traditionally involves complex and time-consuming processes, often relying on trial-and-error methods. The emergence of artificial intelligence, particularly Large Language Models (LLMs), surpassing human c...

End-to-end Chinese clinical event extraction based on large language model.

Scientific reports
Clinical event extraction is crucial for structuring medical data, supporting clinical decision-making, and enabling other intelligent healthcare services. Traditional approaches for clinical event extraction often use pipeline-based methods to ident...

Extracting Multifaceted Characteristics of Patients With Chronic Disease Comorbidity: Framework Development Using Large Language Models.

JMIR medical informatics
BACKGROUND: Research on chronic multimorbidity has increasingly become a focal point with the aging of the population. Many studies in this area require detailed patient characteristic information. However, the current methods for extracting such inf...

Scientific Evidence for Clinical Text Summarization Using Large Language Models: Scoping Review.

Journal of medical Internet research
BACKGROUND: Information overload in electronic health records requires effective solutions to alleviate clinicians' administrative tasks. Automatically summarizing clinical text has gained significant attention with the rise of large language models....

Breaking Digital Health Barriers Through a Large Language Model-Based Tool for Automated Observational Medical Outcomes Partnership Mapping: Development and Validation Study.

Journal of medical Internet research
BACKGROUND: The integration of diverse clinical data sources requires standardization through models such as Observational Medical Outcomes Partnership (OMOP). However, mapping data elements to OMOP concepts demands significant technical expertise an...