Glucose autoxidation has been proposed as a key reaction associated with deleterious effects induced by hyperglycemia in the eye lens. Little is known about chromophores generated during glucose autoxidation. In this study, we analyzed the effect of ...
IEEE transactions on bio-medical engineering
Jun 11, 2015
GOAL: Cataracts are a clouding of the lens and the leading cause of blindness worldwide. Assessing the presence and severity of cataracts is essential for diagnosis and progression monitoring, as well as to facilitate clinical research and management...
Intravital microscopy in small animals growingly contributes to the visualization of short- and long-term mammalian biological processes. Miniaturized fluorescence microscopy has revolutionized the observation of live animals' neural circuits. The te...
PURPOSE: Protein sumoylation is a well established regulatory mechanism that regulates chromatin structure and dynamics, cell proliferation and differentiation, stress response and cell apoptosis. In the vertebrate eye, we and others have shown that ...