AIMC Topic: Lens, Crystalline

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High vacuum and aspiration on phacoemulsification efficiency and chatter for Centurion.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
OBJECTIVE: To compare relative efficiency and chatter of high aspiration and vacuum settings.

The Major Chromophore Arising from Glucose Degradation and Oxidative Stress Occurrence during Lens Proteins Glycation Induced by Glucose.

Molecules (Basel, Switzerland)
Glucose autoxidation has been proposed as a key reaction associated with deleterious effects induced by hyperglycemia in the eye lens. Little is known about chromophores generated during glucose autoxidation. In this study, we analyzed the effect of ...

Automatic Feature Learning to Grade Nuclear Cataracts Based on Deep Learning.

IEEE transactions on bio-medical engineering
GOAL: Cataracts are a clouding of the lens and the leading cause of blindness worldwide. Assessing the presence and severity of cataracts is essential for diagnosis and progression monitoring, as well as to facilitate clinical research and management...

Machine learning Reveals ATM and CNOT6L as critical factors in Cataract pathogenesis.

Experimental eye research
OBJECTIVE: Cataract, a common age-related blinding eye disease, has a complex pathogenesis. This study aims to identify key genes and potential mechanisms associated with cataracts, offering new targets and insights for its prevention and treatment.

Improving flat fluorescence microscopy in scattering tissue through deep learning strategies.

Optics express
Intravital microscopy in small animals growingly contributes to the visualization of short- and long-term mammalian biological processes. Miniaturized fluorescence microscopy has revolutionized the observation of live animals' neural circuits. The te...

Altered Expression Patterns of the Sumoylation Enzymes E1, E2 and E3 Are Associated with Glucose Oxidase- and UVA-Induced Cataractogenesis.

Current molecular medicine
PURPOSE: Protein sumoylation is a well established regulatory mechanism that regulates chromatin structure and dynamics, cell proliferation and differentiation, stress response and cell apoptosis. In the vertebrate eye, we and others have shown that ...