AIMC Topic: Lung Neoplasms

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Predicting lung nodule malignancies by combining deep convolutional neural network and handcrafted features.

Physics in medicine and biology
To predict lung nodule malignancy with a high sensitivity and specificity for low dose CT (LDCT) lung cancer screening, we propose a fusion algorithm that combines handcrafted features (HF) into the features learned at the output layer of a 3D deep c...

Weakly Supervised Deep Learning for Whole Slide Lung Cancer Image Analysis.

IEEE transactions on cybernetics
Histopathology image analysis serves as the gold standard for cancer diagnosis. Efficient and precise diagnosis is quite critical for the subsequent therapeutic treatment of patients. So far, computer-aided diagnosis has not been widely applied in pa...

PET image denoising using unsupervised deep learning.

European journal of nuclear medicine and molecular imaging
PURPOSE: Image quality of positron emission tomography (PET) is limited by various physical degradation factors. Our study aims to perform PET image denoising by utilizing prior information from the same patient. The proposed method is based on unsup...

The effects of physics-based data augmentation on the generalizability of deep neural networks: Demonstration on nodule false-positive reduction.

Medical physics
PURPOSE: An important challenge for deep learning models is generalizing to new datasets that may be acquired with acquisition protocols different from the training set. It is not always feasible to expand training data to the range encountered in cl...

DeepOrganNet: On-the-Fly Reconstruction and Visualization of 3D / 4D Lung Models from Single-View Projections by Deep Deformation Network.

IEEE transactions on visualization and computer graphics
This paper introduces a deep neural network based method, i.e., DeepOrganNet, to generate and visualize fully high-fidelity 3D / 4D organ geometric models from single-view medical images with complicated background in real time. Traditional 3D / 4D m...

Cross-modality (CT-MRI) prior augmented deep learning for robust lung tumor segmentation from small MR datasets.

Medical physics
PURPOSE: Accurate tumor segmentation is a requirement for magnetic resonance (MR)-based radiotherapy. Lack of large expert annotated MR datasets makes training deep learning models difficult. Therefore, a cross-modality (MR-CT) deep learning segmenta...

Automatic Pulmonary Nodule Detection in CT Scans Using Convolutional Neural Networks Based on Maximum Intensity Projection.

IEEE transactions on medical imaging
Accurate pulmonary nodule detection is a crucial step in lung cancer screening. Computer-aided detection (CAD) systems are not routinely used by radiologists for pulmonary nodule detection in clinical practice despite their potential benefits. Maximu...

Multi-Task Deep Model With Margin Ranking Loss for Lung Nodule Analysis.

IEEE transactions on medical imaging
Lung cancer is the leading cause of cancer deaths worldwide and early diagnosis of lung nodule is of great importance for therapeutic treatment and saving lives. Automated lung nodule analysis requires both accurate lung nodule benign-malignant class...

Lung segmentation method with dilated convolution based on VGG-16 network.

Computer assisted surgery (Abingdon, England)
Lung cancer has become one of the life-threatening killers. Lung disease need to be assisted by CT images taken doctor's diagnosis, and the segmented CT image of the lung parenchyma is the first step to help doctor diagnosis. For the problem of accur...

An investigation of CNN models for differentiating malignant from benign lesions using small pathologically proven datasets.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Cancer has been one of the most threatening diseases to human health. There have been many efforts devoted to the advancement of radiology and transformative tools (e.g. non-invasive computed tomographic or CT imaging) to detect cancer in early stage...