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Drive Pressure-Guided Individualized Positive End-Expiratory Pressure in Traumatic Brain Injury Surgery: A Randomized Controlled Trial.

Annali italiani di chirurgia
AIM: Intraoperative lung-protective ventilation strategies (LPVS) have been shown to improve lung oxygenation and prevent postoperative pulmonary problems in surgical patients. However, the application of positive end-expiratory pressure (PEEP)-based...

Artificial Intelligence Assessment of Chest Radiographs for COVID-19.

Clinical lymphoma, myeloma & leukemia
BACKGROUND: The sensitivity of reverse-transcription polymerase chain reaction (RT-PCR) is limited for diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Chest computed tomography (CT) is reported to have high sensitivity; how...

Machine learning identifies remodeling patterns in human lung extracellular matrix.

Acta biomaterialia
Organ function depends on the three-dimensional integrity of the extracellular matrix (ECM). The structure resulting from the location and association of ECM components is a central regulator of cell behavior, but a dearth of matrix-specific analysis...

Sub-millimeter fiberscopic robot with integrated maneuvering, imaging, and biomedical operation abilities.

Nature communications
Small-scale continuum robots hold promise for interventional diagnosis and treatment, yet existing models struggle to achieve small size, precise steering, and visualized functional treatment simultaneously, termed an "impossible trinity". This study...

Noninvasive estimation of PaCO from volumetric capnography in animals with injured lungs: an Artificial Intelligence approach.

Journal of clinical monitoring and computing
To investigate the feasibility of non-invasively estimating the arterial partial pressure of carbon dioxide (PaCO) using a computational Adaptive Neuro-Fuzzy Inference System (ANFIS) model fed by noninvasive volumetric capnography (VCap) parameters. ...

Automated measurement of cardiothoracic ratio based on semantic segmentation integration model using deep learning.

Medical & biological engineering & computing
The objective of this study is to investigate the efficacy of the semantic segmentation model in predicting cardiothoracic ratio (CTR) and heart enlargement and compare its consistency with the reference standard. A total of 650 consecutive chest rad...

Optimizing convolutional neural networks for Chronic Obstructive Pulmonary Disease detection in clinical computed tomography imaging.

Computers in biology and medicine
We aim to optimize the binary detection of Chronic Obstructive Pulmonary Disease (COPD) based on emphysema presence in the lung with convolutional neural networks (CNN) by exploring manually adjusted versus automated window-setting optimization (WSO)...

Diagnosis of Fibrotic Interstitial Lung Diseases Based on the Combination of Label-Free Quantitative Multiphoton Fiber Histology and Machine Learning.

Laboratory investigation; a journal of technical methods and pathology
Interstitial lung disease (ILD), characterized by inflammation and fibrosis, often suffers from low diagnostic accuracy and consistency. Traditional hematoxylin and eosin (H&E) staining primarily reveals cellular inflammation with limited detail on f...

Evaluating the Cumulative Benefit of Inspiratory CT, Expiratory CT, and Clinical Data for COPD Diagnosis and Staging through Deep Learning.

Radiology. Cardiothoracic imaging
Purpose To measure the benefit of single-phase CT, inspiratory-expiratory CT, and clinical data for convolutional neural network (CNN)-based chronic obstructive pulmonary disease (COPD) staging. Materials and Methods This retrospective study included...