AIMC Topic: Machine Learning

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Nonionic surfactant Tween 80-facilitated bacterial transport in porous media: A nonmonotonic concentration-dependent performance, mechanism, and machine learning prediction.

Environmental research
The surfactant-enhanced bioremediation (SEBR) of organic-contaminated soil is a promising soil remediation technology, in which surfactants not only mobilize pollutants, but also alter the mobility of bacteria. However, the bacterial response and und...

Predicting the onset of end-stage knee osteoarthritis over two- and five-years using machine learning.

Seminars in arthritis and rheumatism
OBJECTIVE: Identifying participants who will progress to advanced stage in knee osteoarthritis (KOA) trials remains a significant challenge. Current tools, relying on total knee replacements (TKR), fall short in reliability due to the extraneous fact...

Mortality risk prediction for primary appendiceal cancer.

Surgery
BACKGROUND: Accurately predicting survival in patients with cancer is crucial for both clinical decision-making and patient counseling. The primary aim of this study was to generate the first machine-learning algorithm to predict the risk of mortalit...

EPDRNA: A Model for Identifying DNA-RNA Binding Sites in Disease-Related Proteins.

The protein journal
Protein-DNA and protein-RNA interactions are involved in many biological processes and regulate many cellular functions. Moreover, they are related to many human diseases. To understand the molecular mechanism of protein-DNA binding and protein-RNA b...

PPII-AEAT: Prediction of protein-protein interaction inhibitors based on autoencoders with adversarial training.

Computers in biology and medicine
Protein-protein interactions (PPIs) have shown increasing potential as novel drug targets. The design and development of small molecule inhibitors targeting specific PPIs are crucial for the prevention and treatment of related diseases. Accordingly, ...

Optimization of Ganciclovir and Valganciclovir Starting Dose in Children by Machine Learning.

Clinical pharmacokinetics
BACKGROUND AND OBJECTIVES: Ganciclovir (GCV) and valganciclovir (VGCV) show large interindividual pharmacokinetic variability, particularly in children. The objectives of this study were (1) to develop machine learning (ML) algorithms trained on simu...

PAR-Net: An Enhanced Dual-Stream CNN-ESN Architecture for Human Physical Activity Recognition.

Sensors (Basel, Switzerland)
Physical exercise affects many facets of life, including mental health, social interaction, physical fitness, and illness prevention, among many others. Therefore, several AI-driven techniques have been developed in the literature to recognize human ...

Using protein language models for protein interaction hot spot prediction with limited data.

BMC bioinformatics
BACKGROUND: Protein language models, inspired by the success of large language models in deciphering human language, have emerged as powerful tools for unraveling the intricate code of life inscribed within protein sequences. They have gained signifi...