Computational and mathematical methods in medicine
Dec 8, 2021
One of the most common visual disorders is cataracts, which people suffer from as they get older. The creation of a cloud on the lens of our eyes is known as a cataract. Blurred vision, faded colors, and difficulty seeing in strong light are the main...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
The advancements of single-cell RNA sequencing (scRNA-seq) technologies have provided us unprecedented opportunities to characterize cellular states and investigate the mechanisms of complex diseases. Due to technical issues such as dropout events, s...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
Non-coding RNA (ncRNA) is involved in many biological processes and diseases in all species. Many ncRNA datasets exist that provide ncRNA data in FASTA format which is well suited for biomedical purposes. However, for ncRNA analysis and classificatio...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
Myocardial infarctions and heart failure are the cause of more than 17 million deaths annually worldwide. ST-segment elevation myocardial infarctions (STEMI) require timely treatment, because delays of minutes have serious clinical impacts. Machine l...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
Protein fold recognition is critical for studies of the protein structure prediction and drug design. Several methods have been proposed to obtain discriminative features from the protein sequences for fold recognition. However, the ensemble methods ...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
Identifying interactions between drugs and target proteins is a critical step in the drug development process, as it helps identify new targets for drugs and accelerate drug development. The number of known drug-protein interactions (positive samples...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
Understanding the ageing process is a very challenging problem for biologists. To help in this task, there has been a growing use of classification methods (from machine learning) to learn models that predict whether a gene influences the process of ...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
Molecular biomarkers are certain molecules or set of molecules that can be of help for diagnosis or prognosis of diseases or disorders. In the past decades, thanks to the advances in high-throughput technologies, a huge amount of molecular 'omics' da...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
The global alignment of biological networks (GABN) aims to find an optimal alignment between proteins across species, such that both the biological structures and the topological structures of the proteins are maximally conserved. The research on GAB...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2021
Protein Secondary Structural Class (PSSC) information is important in investigating further challenges of protein sequences like protein fold recognition, protein tertiary structure prediction, and analysis of protein functions for drug discovery. Id...
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