There is increasing interest in developing diagnostics that discriminate individual mutagenic mechanisms in a range of applications that include identifying population-specific mutagenesis and resolving distinct mutation signatures in cancer samples....
INTRODUCTION: Adductor-type spasmodic dysphonia is a task-specific focal dystonia characterized by involuntary laryngeal muscle spasms. Due to the lack of quantitative instrumental tools, voice assessment in patients with adductor-type spasmodic dysp...
International journal of molecular sciences
Mar 19, 2020
Drug-induced liver injury (DILI) remains one of the challenges in the safety profile of both authorized and candidate drugs, and predicting hepatotoxicity from the chemical structure of a substance remains a task worth pursuing. Such an approach is c...
The Internet of Things (IoT) is widely applied in modern human life, e.g., smart home and intelligent transportation. However, it is vulnerable to malicious attacks, and the current existing security mechanisms cannot completely protect the IoT. As a...
Recently, significant attention has been devoted to vaccine-derived poliovirus (VDPV) surveillance due to its severe consequences. Prediction of the outbreak incidence of VDPF requires an accurate analysis of the alarming data. The overarching aim to...
In recent years machine learning (ML) took bio- and cheminformatics fields by storm, providing new solutions for a vast repertoire of problems related to protein sequence, structure, and interactions analysis. ML techniques, deep neural networks espe...
Autism has become a pressing healthcare challenge. The instruments used to aid diagnosis are time and labor expensive and require trained clinicians to administer, leading to long wait times for at-risk children. We present a multi-modular, machine l...
Develop a machine learning-based method to generate multi-contrast anatomical textures in the 4D extended cardiac-torso (XCAT) phantom for more realistic imaging simulations. As a pilot study, we synthesize CT and CBCT textures in the chest region. F...
There has been a tidal wave of recent interest in artificial intelligence (AI), machine learning and deep learning approaches in cardiovascular (CV) medicine. In the era of modern medicine, AI and electronic health records hold the promise to improve...
Multilayer neural networks have led to remarkable performance on many kinds of benchmark tasks in text, speech, and image processing. Nonlinear parameter estimation in hierarchical models is known to be subject to overfitting and misspecification. On...
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